SCHEMBL8990537

SCHEMBL8990537

CCCC[Si](C)(C)Oc1cc2c(cc1O[Si](C)(C)CCCC)C(c1ccc(N(C)C)cc1)CC2

nearest known ligand 0.40

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.40
HCRTR1 O43613 1/20 0.35
HCRTR2 O43614 1/20 0.35
ALDH1A1 P00352 1/20 0.34
MAPK1 P28482 1/20 0.34
SLC10A2 Q12908 7/20 0.32
MDM4 O15151 1/20 0.31
TP53 P04637 1/20 0.31
MDM2 Q00987 1/20 0.31
CRBN Q96SW2 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8938866 0.80 GAA (0.43) GAAALDH1A1MAPK1MDM4TP53
SCHEMBL8938880 0.69 IGF1R (0.54) GAAALDH1A1MAPK1
SCHEMBL28129775 0.65 SIGMAR1 (0.55) ALDH1A1MAPK1
SCHEMBL8990389 0.62 MAOB (0.35) ALDH1A1MAPK1
SCHEMBL27880552 0.62 CYP26A1 (0.39) ALDH1A1
SCHEMBL10321209 0.61 ALDH1A1 (0.39) GAAALDH1A1MAPK1TP53
SCHEMBL8085206 0.59 SLC6A2 (0.44)
SCHEMBL30789061 0.58 GAA (0.97) GAAALDH1A1MAPK1
SCHEMBL30789060 0.58 GAA (0.97) GAAALDH1A1MAPK1
SCHEMBL27745410 0.57 CYP4F2 (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0625209-B1 METHOD FOR ASSAYING THE SOD ACTIVITY BY USING A SELF- OXIDIZABLE COMPOUND NECESSARY FOR ITS IMPLEMENTATION, SELF- OXIDIZABLE COMPOUNDS AND PREPARATION THEREOF OXIS INT SA (FR) 1996-07-17 EP disclosed