Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8939030 | 0.91 | TSHR (0.40) | HPGDTDP1MEN1KMT2AHTT | |
| SCHEMBL8939017 | 0.86 | MAPT (0.37) | HPGDNPC1TP53RAB9ATDP1 | |
| SCHEMBL8938993 | 0.85 | MEN1 (0.42) | HPGDNPC1RAB9ATDP1MEN1 | |
| SCHEMBL8938989 | 0.85 | KMT2A (0.37) | HPGDTP53HSD17B10POLBMEN1 | |
| SCHEMBL713632 | 0.85 | HPGD (0.43) | HPGDTDP1MEN1KMT2AALDH1A1 | |
| SCHEMBL8939023 | 0.82 | HPGD (0.44) | HPGDTDP1POLBMEN1KMT2A | |
| SCHEMBL8938998 | 0.82 | SMN1; SMN2 (0.36) | HPGDNPC1RAB9AHSD17B10MEN1 | |
| SCHEMBL8939000 | 0.82 | ATM (0.39) | TDP1MEN1KMT2AALDH1A1 | |
| SCHEMBL710803 | 0.81 | POLB (0.38) | HPGDTDP1POLBMEN1KMT2A | |
| SCHEMBL8939025 | 0.81 | APEX1 (0.37) | MRGPRX4TDP1MEN1KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0600373-A1 | Alkyl-arylesters of arylphosphonous acid process for their preparation and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-06-08 | — | — | EP | claimed |
| US-5498741-A | Alkyl aryl arylphosphonites, process for the preparation thereof and use thereof | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-03-12 | — | — | US | disclosed |
| EP-0600373-A1 | Alkyl-arylesters of arylphosphonous acid process for their preparation and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-06-08 | — | — | EP | disclosed |