Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | TTR | P02766 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8939019 | 0.91 | HPGD (0.38) | CYP2C9HTTMEN1KMT2AMAPT | |
| SCHEMBL8939017 | 0.85 | MAPT (0.37) | TSHRCYP2C9LMNAMEN1KMT2A | |
| SCHEMBL8938993 | 0.84 | MEN1 (0.42) | TSHRLMNAMEN1KMT2AMAPT | |
| SCHEMBL8938989 | 0.83 | KMT2A (0.37) | HTTLMNAMEN1KMT2AMAPT | |
| SCHEMBL713632 | 0.83 | HPGD (0.43) | LMNAMEN1KMT2AHCRTR1HPGD | |
| SCHEMBL8939023 | 0.81 | HPGD (0.44) | TSHRLMNAMEN1KMT2AMAPT | |
| SCHEMBL8938998 | 0.81 | SMN1; SMN2 (0.36) | LMNAMEN1KMT2AMAPTHPGD | |
| SCHEMBL8939000 | 0.81 | ATM (0.39) | LMNAMEN1KMT2ATDP1KDM4E | |
| SCHEMBL710803 | 0.80 | POLB (0.38) | HTTLMNAMEN1KMT2AMAPT | |
| SCHEMBL22172022 | 0.79 | ABCB1 (0.36) | HTTLMNAMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0600373-A1 | Alkyl-arylesters of arylphosphonous acid process for their preparation and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-06-08 | — | — | EP | claimed |
| US-5498741-A | Alkyl aryl arylphosphonites, process for the preparation thereof and use thereof | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-03-12 | — | — | US | disclosed |
| EP-0600373-A1 | Alkyl-arylesters of arylphosphonous acid process for their preparation and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-06-08 | — | — | EP | disclosed |