Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8939023 | 0.94 | HPGD (0.44) | MEN1KMT2ALMNACYP3A4TSHR | |
| SCHEMBL713632 | 0.94 | HPGD (0.43) | MEN1KMT2ALMNAHPGDHCRTR1 | |
| SCHEMBL8938991 | 0.92 | PKM (0.43) | LMNAHPGDMAPTNPSR1NPC1 | |
| SCHEMBL8939048 | 0.91 | MEN1 (0.40) | MEN1KMT2ALMNACYP3A4TSHR | |
| SCHEMBL8939044 | 0.88 | PKM (0.42) | MEN1KMT2ALMNAHPGDHCRTR1 | |
| SCHEMBL8938989 | 0.86 | KMT2A (0.37) | MEN1KMT2ALMNAHPGDMAPT | |
| SCHEMBL8939019 | 0.85 | HPGD (0.38) | MEN1KMT2ACYP3A4HPGDMAPT | |
| SCHEMBL8938996 | 0.84 | ALDH1A1 (0.41) | MEN1KMT2ALMNACYP3A4MAPT | |
| SCHEMBL8939030 | 0.84 | TSHR (0.40) | MEN1KMT2ALMNATSHRHPGD | |
| SCHEMBL8938998 | 0.83 | SMN1; SMN2 (0.36) | MEN1KMT2ALMNAHPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0600373-A1 | Alkyl-arylesters of arylphosphonous acid process for their preparation and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-06-08 | — | — | EP | claimed |
| US-5498741-A | Alkyl aryl arylphosphonites, process for the preparation thereof and use thereof | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-03-12 | — | — | US | disclosed |
| EP-0600373-A1 | Alkyl-arylesters of arylphosphonous acid process for their preparation and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-06-08 | — | — | EP | disclosed |