Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CRHBP | P24387 | 1/20 | 0.37 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8939019 | 0.86 | HPGD (0.38) | MAPTKMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL8939030 | 0.85 | TSHR (0.40) | MAPTKMT2AMEN1LMNASMN1; SMN2 | |
| SCHEMBL8939023 | 0.85 | HPGD (0.44) | MAPTKMT2AMEN1LMNAALDH1A1 | |
| SCHEMBL8938993 | 0.82 | MEN1 (0.42) | MAPTKMT2AMEN1LMNAALDH1A1 | |
| SCHEMBL3242585 | 0.80 | LMNA (0.40) | MAPTKMT2AMEN1LMNASMN1; SMN2 | |
| SCHEMBL8939000 | 0.80 | ATM (0.39) | KMT2AMEN1LMNAALDH1A1TDP1 | |
| SCHEMBL8938998 | 0.80 | SMN1; SMN2 (0.36) | MAPTKMT2AMEN1LMNAALDH1A1 | |
| SCHEMBL8938989 | 0.79 | KMT2A (0.37) | MAPTKMT2AMEN1LMNASMN1; SMN2 | |
| SCHEMBL713632 | 0.79 | HPGD (0.43) | KMT2AMEN1LMNAALDH1A1TDP1 | |
| SCHEMBL8939044 | 0.76 | PKM (0.42) | KMT2AMEN1LMNAALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5498741-A | Alkyl aryl arylphosphonites, process for the preparation thereof and use thereof | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-03-12 | — | — | US | disclosed |