Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.37 |
| ▸ | MEN1 | O00255 | 7/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8938998 | 0.94 | SMN1; SMN2 (0.36) | KMT2AMEN1ATMLMNAHPGD | |
| SCHEMBL713632 | 0.88 | HPGD (0.43) | KMT2AMEN1LMNAHPGDSRC | |
| SCHEMBL8938993 | 0.86 | MEN1 (0.42) | KMT2AMEN1LMNAHPGDGAA | |
| SCHEMBL710803 | 0.85 | POLB (0.38) | KMT2AMEN1LMNAHTTHPGD | |
| SCHEMBL8939019 | 0.85 | HPGD (0.38) | KMT2AMEN1HTTHPGDTP53 | |
| SCHEMBL22172022 | 0.84 | ABCB1 (0.36) | KMT2AMEN1ATMLMNAHTT | |
| SCHEMBL8938991 | 0.83 | PKM (0.43) | LMNAHTTHPGDMAPTPOLB | |
| SCHEMBL8939030 | 0.83 | TSHR (0.40) | KMT2AMEN1LMNAHTTHPGD | |
| SCHEMBL8939023 | 0.83 | HPGD (0.44) | KMT2AMEN1LMNAHPGDGAA | |
| SCHEMBL21790454 | 0.82 | POLB (0.36) | KMT2AMEN1ATMLMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0600373-A1 | Alkyl-arylesters of arylphosphonous acid process for their preparation and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-06-08 | — | — | EP | claimed |
| US-5498741-A | Alkyl aryl arylphosphonites, process for the preparation thereof and use thereof | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-03-12 | — | — | US | disclosed |
| EP-0600373-A1 | Alkyl-arylesters of arylphosphonous acid process for their preparation and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-06-08 | — | — | EP | disclosed |