Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | SRC | P12931 | 1/20 | 0.42 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL713632 | 0.88 | HPGD (0.43) | L3MBTL1TDP1LMNAMEN1KMT2A | |
| SCHEMBL8939049 | 0.84 | TDP1 (0.44) | L3MBTL1TDP1LMNAMEN1KMT2A | |
| SCHEMBL2770323 | 0.84 | POLB (0.40) | L3MBTL1TDP1LMNAMEN1KMT2A | |
| SCHEMBL8939023 | 0.82 | HPGD (0.44) | L3MBTL1TDP1LMNAMEN1KMT2A | |
| SCHEMBL8938993 | 0.82 | MEN1 (0.42) | L3MBTL1TDP1LMNAMEN1KMT2A | |
| SCHEMBL8939045 | 0.81 | ACHE (0.41) | LMNAMEN1KMT2APKMHTT | |
| SCHEMBL8938991 | 0.80 | PKM (0.43) | TDP1LMNAPKMHTTHPGD | |
| SCHEMBL7624661 | 0.80 | ALDH1A1 (0.50) | L3MBTL1LMNAMEN1KMT2AHTT | |
| SCHEMBL8938998 | 0.80 | SMN1; SMN2 (0.36) | L3MBTL1LMNAMEN1KMT2AHPGD | |
| SCHEMBL8939044 | 0.79 | PKM (0.42) | L3MBTL1TDP1LMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0600373-A1 | Alkyl-arylesters of arylphosphonous acid process for their preparation and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-06-08 | — | — | EP | claimed |
| US-5498741-A | Alkyl aryl arylphosphonites, process for the preparation thereof and use thereof | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-03-12 | — | — | US | disclosed |
| EP-0600373-A1 | Alkyl-arylesters of arylphosphonous acid process for their preparation and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-06-08 | — | — | EP | disclosed |