Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | RXRA | P19793 | 1/20 | 0.38 |
| ▸ | RXRB | P28702 | 1/20 | 0.38 |
| ▸ | RXRG | P48443 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | RBP4 | P02753 | 2/20 | 0.34 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | NAMPT | P43490 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8938990 | 0.88 | CYP1A2 (0.40) | MAPTTP53ALDH1A1KDM4EGAA | |
| SCHEMBL3418456 | 0.87 | TDP1 (0.42) | MAPTTP53ALDH1A1KDM4EGAA | |
| SCHEMBL8939034 | 0.84 | APEX1 (0.35) | MAPTALDH1A1KDM4ECYP1A2CYP2D6 | |
| SCHEMBL13199352 | 0.81 | TDP1 (0.39) | MAPTTP53ALDH1A1KDM4EGAA | |
| SCHEMBL28363499 | 0.76 | TDP1 (0.42) | MAPTTP53ALDH1A1KDM4EGAA | |
| SCHEMBL911476 | 0.75 | CYP3A4 (0.39) | TP53ALDH1A1TDP1HSD17B10NPSR1 | |
| SCHEMBL8939051 | 0.74 | LTA4H (0.39) | TDP1LMNAGLAL3MBTL1TSHR | |
| SCHEMBL31556872 | 0.74 | TDP1 (0.36) | MAPTTP53ALDH1A1KDM4EGAA | |
| SCHEMBL2368433 | 0.73 | TDP1 (0.41) | MAPTTP53ALDH1A1KDM4EGAA | |
| SCHEMBL27772030 | 0.73 | NAMPT (0.44) | MAPTTP53ALDH1A1KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5498741-A | Alkyl aryl arylphosphonites, process for the preparation thereof and use thereof | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-03-12 | — | — | US | disclosed |