Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | RXRA | P19793 | 1/20 | 0.40 |
| ▸ | RXRB | P28702 | 1/20 | 0.40 |
| ▸ | RXRG | P48443 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.36 |
| ▸ | RBP4 | P02753 | 3/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13199352 | 0.93 | TDP1 (0.39) | TDP1ATMMAPTTP53ALDH1A1 | |
| SCHEMBL8939054 | 0.87 | MAPT (0.38) | TDP1ATMMAPTTP53ALDH1A1 | |
| SCHEMBL31556872 | 0.86 | TDP1 (0.36) | TDP1ATMMAPTTP53ALDH1A1 | |
| SCHEMBL28363499 | 0.85 | TDP1 (0.42) | TDP1ATMMAPTTP53ALDH1A1 | |
| SCHEMBL8938990 | 0.84 | CYP1A2 (0.40) | TDP1ATMMAPTTP53ALDH1A1 | |
| SCHEMBL10309813 | 0.83 | TDP1 (0.33) | TDP1ATMMAPTTP53ALDH1A1 | |
| SCHEMBL8360217 | 0.82 | CA2 (0.40) | TDP1ATMALDH1A1KDM4EGAA | |
| SCHEMBL27772030 | 0.81 | NAMPT (0.44) | TDP1ATMMAPTTP53ALDH1A1 | |
| SCHEMBL2368433 | 0.81 | TDP1 (0.41) | TDP1ATMMAPTTP53ALDH1A1 | |
| SCHEMBL7115234 | 0.81 | APEX1 (0.39) | TDP1MAPTALDH1A1KDM4ECYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7851656-B2 | Method for producing organic phosphorous compounds containing halogens | BASF SE (DE) | 2010-12-14 | — | — | US | disclosed |
| US-7851656-B2 | Method for producing organic phosphorous compounds containing halogens | BASF SE (DE) | 2010-12-14 | — | — | US | disclosed |
| US-20100252786-A1 | CELLULOSE ESTER FILM, METHOD OF MANUFACTURING THE SAME, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY | KONICA MINOLTA OPTO, INC. (JP) | 2010-10-07 | — | — | US | disclosed |
| US-20100103352-A1 | OPTICAL FILM, POLARIZING PLATE, LIQUID CRYSTAL DISPLAY AND ULTRAVIOLET ABSORBING POLYMER | KONICA MINOLTA OPTO, INC. (JP) | 2010-04-29 | — | — | US | disclosed |
| US-20090281356-A1 | METHOD FOR PRODUCING ORGANIC PHOSPHOROUS COMPOUNDS CONTAINING HALOGENE | BASF SE (DE) | 2009-11-12 | — | — | US | disclosed |
| US-20090281356-A1 | METHOD FOR PRODUCING ORGANIC PHOSPHOROUS COMPOUNDS CONTAINING HALOGENE | BASF SE (DE) | 2009-11-12 | — | — | US | disclosed |
| WO-2008006735-A1 | METHOD FOR PRODUCING ORGANIC PHOSPHOROUS COMPOUNDS CONTAINING HALOGENE | BASF SE (DE) | 2008-01-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090281356-A1 | METHOD FOR PRODUCING ORGANIC PHOSPHOROUS COMPOUNDS CONTAINING HALOGENE | PRXL2A, XRN2, POLR2B | TDP1 1546/4885ATM 3382/4885MAPT 4384/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.