Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | RXRA | P19793 | 1/20 | 0.36 |
| ▸ | RXRB | P28702 | 1/20 | 0.36 |
| ▸ | RXRG | P48443 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | RBP4 | P02753 | 3/20 | 0.33 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3418456 | 0.93 | TDP1 (0.42) | TDP1ATMMAPTTP53ALDH1A1 | |
| SCHEMBL8939054 | 0.81 | MAPT (0.38) | TDP1ATMMAPTTP53ALDH1A1 | |
| SCHEMBL31556872 | 0.80 | TDP1 (0.36) | TDP1ATMMAPTTP53ALDH1A1 | |
| SCHEMBL10309813 | 0.80 | TDP1 (0.33) | TDP1ATMMAPTTP53ALDH1A1 | |
| SCHEMBL28363499 | 0.79 | TDP1 (0.42) | TDP1ATMMAPTTP53ALDH1A1 | |
| SCHEMBL8938990 | 0.78 | CYP1A2 (0.40) | TDP1ATMMAPTTP53ALDH1A1 | |
| SCHEMBL8360217 | 0.77 | CA2 (0.40) | TDP1ATMALDH1A1KDM4EGAA | |
| SCHEMBL12809508 | 0.76 | IDO1 (0.32) | TDP1ATMIDO1 | |
| SCHEMBL27772030 | 0.76 | NAMPT (0.44) | TDP1ATMMAPTTP53ALDH1A1 | |
| SCHEMBL2368433 | 0.76 | TDP1 (0.41) | TDP1ATMMAPTTP53ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10035756-B2 | Integrated process for nitrile manufacture with enhanced liquid-liquid extraction | INVISTA NORTH AMERICA S.A.R.L. (US) | 2018-07-31 | — | — | US | disclosed |
| US-10035756-B2 | Integrated process for nitrile manufacture with enhanced liquid-liquid extraction | INVISTA NORTH AMERICA S.A.R.L. (US) | 2018-07-31 | — | — | US | disclosed |
| US-9914700-B2 | Enhanced extraction of impurities from mixture comprising nitriles | INVISTA NORTH AMERICA S.A R.L. (US) | 2018-03-13 | — | — | US | disclosed |
| US-9914700-B2 | Enhanced extraction of impurities from mixture comprising nitriles | INVISTA NORTH AMERICA S.A R.L. (US) | 2018-03-13 | — | — | US | disclosed |
| US-20170197909-A1 | ENHANCED EXTRACTION OF IMPURITIES FROM MIXTURE COMPRISING NITRILES | INVISTA NORTH AMERICA S.A R.L. (US) | 2017-07-13 | — | — | US | disclosed |
| US-20170197909-A1 | ENHANCED EXTRACTION OF IMPURITIES FROM MIXTURE COMPRISING NITRILES | INVISTA NORTH AMERICA S.A R.L. (US) | 2017-07-13 | — | — | US | disclosed |
| US-9676800-B2 | Extraction solvent control for reducing stable emulsions | INVISTA NORTH AMERICA S.A.R.L. (US) | 2017-06-13 | — | — | US | disclosed |
| US-9676800-B2 | Extraction solvent control for reducing stable emulsions | INVISTA NORTH AMERICA S.A.R.L. (US) | 2017-06-13 | — | — | US | disclosed |
| US-20170152211-A1 | INTEGRATED PROCESS FOR NITRILE MANUFACTURE WITH ENHANCED LIQUID-LIQUID EXTRACTION | INVISTA NORTH AMERICA S.A R.L. (US) | 2017-06-01 | — | — | US | disclosed |
| US-20170152211-A1 | INTEGRATED PROCESS FOR NITRILE MANUFACTURE WITH ENHANCED LIQUID-LIQUID EXTRACTION | INVISTA NORTH AMERICA S.A R.L. (US) | 2017-06-01 | — | — | US | disclosed |
| EP-1472201-B1 | METHOD FOR THE SEPARATION OF ACIDS FROM CHEMICAL REACTION MIXTURES BY MEANS OF IONIC FLUIDS | BASF SE (DE) | 2014-08-13 | — | — | EP | disclosed |
| US-7767852-B2 | Removal by salt formation | BASF AKTIENGESELLSCHAFT (DE) | 2010-08-03 | — | — | US | disclosed |
| US-7767852-B2 | Removal by salt formation | BASF AKTIENGESELLSCHAFT (DE) | 2010-08-03 | — | — | US | disclosed |
| US-7550407-B2 | System suitable for the hydrocyanation of olefinically unsaturated compounds | BASF AKTIENGESELLSCHAFT (DE) | 2009-06-23 | — | — | US | disclosed |
| US-7550407-B2 | System suitable for the hydrocyanation of olefinically unsaturated compounds | BASF AKTIENGESELLSCHAFT (DE) | 2009-06-23 | — | — | US | disclosed |
| US-20080083606-A1 | preparing aminodihalophosphines, diaminohalophosphines, triaminophosphines, phosphorous ester diamides, aminophosphines, diaminophosphines, phosphorous ester amide halides and aminophosphine halides with elimination of an acid in the presence of an auxiliary base | BASF AKTIENGESELLSCHAFT (DE) | 2008-04-10 | — | — | US | disclosed |
| US-20080083606-A1 | preparing aminodihalophosphines, diaminohalophosphines, triaminophosphines, phosphorous ester diamides, aminophosphines, diaminophosphines, phosphorous ester amide halides and aminophosphine halides with elimination of an acid in the presence of an auxiliary base | BASF AKTIENGESELLSCHAFT (DE) | 2008-04-10 | — | — | US | disclosed |
| US-7351339-B2 | Using an auxiliary base to form a salt with the acid which is liquid at low enough temperature so that value product does not decompose during the removal of the liquid salt; e.g. acid catalyst removal; ionic liquids | BASF AKTIENGESELLSCHAFT (DE) | 2008-04-01 | — | — | US | disclosed |
| US-7351339-B2 | Using an auxiliary base to form a salt with the acid which is liquid at low enough temperature so that value product does not decompose during the removal of the liquid salt; e.g. acid catalyst removal; ionic liquids | BASF AKTIENGESELLSCHAFT (DE) | 2008-04-01 | — | — | US | disclosed |
| EP-1610893-B1 | SYSTEM SUITABLE FOR THE HYDROCYANATION OF OLEFINICALLY UNSATURATED COMPOUNDS | BASF AG (DE) | 2007-03-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170197909-A1 | ENHANCED EXTRACTION OF IMPURITIES FROM MIXTURE COMPRISING NITRILES | NCL, BMP4, ALPL | TDP1 941/4885ATM 1687/4885MAPT 3372/4885 |
| US-10035756-B2 | Integrated process for nitrile manufacture with enhanced liquid-liquid extraction | BHMT, HNMT, PNMT | TDP1 1512/4885ATM 986/4885MAPT 910/4885 |
| US-20170152211-A1 | INTEGRATED PROCESS FOR NITRILE MANUFACTURE WITH ENHANCED LIQUID-LIQUID EXTRACTION | BHMT, HNMT, ALKBH3 | TDP1 1671/4885ATM 928/4885MAPT 997/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.