Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | STAT6 | P42226 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8939608 | 1.00 | ALDH1A1 (0.44) | ALDH1A1MAPTL3MBTL1LMNAGAA | |
| SCHEMBL8939658 | 1.00 | ALDH1A1 (0.44) | ALDH1A1MAPTL3MBTL1LMNAGAA | |
| SCHEMBL8939645 | 0.83 | KMT2A (0.55) | ALDH1A1LMNAKMT2AMEN1CYP3A4 | |
| SCHEMBL8939654 | 0.83 | ALDH1A1 (0.51) | ALDH1A1MAPTL3MBTL1LMNAGAA | |
| SCHEMBL8939701 | 0.83 | ALDH1A1 (0.51) | ALDH1A1MAPTL3MBTL1LMNAGAA | |
| SCHEMBL8939610 | 0.83 | ALDH1A1 (0.51) | ALDH1A1MAPTL3MBTL1LMNAGAA | |
| SCHEMBL9019620 | 0.82 | KDM4E (0.40) | ALDH1A1MAPTLMNAGAAKMT2A | |
| SCHEMBL8939597 | 0.82 | LMNA (0.46) | ALDH1A1MAPTLMNAGAAKMT2A | |
| SCHEMBL8939603 | 0.76 | TSHR (0.48) | ALDH1A1MAPTLMNAGAAKMT2A | |
| SCHEMBL8939673 | 0.76 | LMNA (0.50) | ALDH1A1MAPTLMNAGAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0626369-B1 | BENZENESULFONAMIDE DERIVATIVE | KYOWA HAKKO KOGYO KK (JP) | 1996-09-18 | — | — | EP | disclosed |
| US-5523464-A | BONE DISORDERS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1996-06-04 | — | — | US | disclosed |
| EP-0626369-A1 | BENZENESULFONAMIDE DERIVATIVE | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1994-11-30 | — | — | EP | disclosed |