Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.43 |
| ▸ | IDO1 | P14902 | 2/20 | 0.39 |
| ▸ | AGXT | P21549 | 2/20 | 0.39 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL79754 | 0.87 | CALM1 (0.50) | IDO1LMNATSHRCALM1ALDH1A1 | |
| SCHEMBL7705052 | 0.87 | CYP1A2 (0.43) | TAAR1IDO1LMNAHTTALDH1A1 | |
| SCHEMBL8791282 | 0.80 | ESR1 (0.50) | TAAR1IDO1LMNAPTGS1CA2 | |
| SCHEMBL17956849 | 0.80 | CYP3A4 (0.50) | LMNAGAATSHRCA12CA1 | |
| SCHEMBL27490282 | 0.80 | TP53 (0.44) | TAAR1LMNACALM1ALDH1A1MGLL | |
| SCHEMBL6353303 | 0.80 | IDO1 (0.37) | TAAR1IDO1AGXTLMNATSHR | |
| SCHEMBL1531987 | 0.80 | IDO1 (0.37) | TAAR1IDO1AGXTLMNACALM1 | |
| SCHEMBL4390802 | 0.80 | APP (0.37) | IDO1CALM1 | |
| SCHEMBL1531966 | 0.80 | SIGMAR1 (0.37) | TAAR1IDO1LMNAALDH1A1MEN1 | |
| SCHEMBL28044480 | 0.80 | TSHR (0.44) | TSHRCA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1306515-A | Combinations of protein farnesyltransferase and HMG COA reductase inhibitors and their use to treat cancer | WARNER LAMBERT CO (US) | 2001-08-01 | — | — | CN | claimed |
| CN-1306515-A | Combinations of protein farnesyltransferase and HMG COA reductase inhibitors and their use to treat cancer | WARNER LAMBERT CO (US) | 2001-08-01 | — | — | CN | disclosed |
| CN-1291739-A | Chinese-character 'returning dummy roots to zero' input method | GUO YONGAN (CN) | 2001-04-18 | — | — | CN | disclosed |
| US-5516797-A | SUPPRESSING GRAFT REJECTION | VERTEX PHARMACEUTICALS, INCORPORATED (US) | 1996-05-14 | — | — | US | disclosed |
| US-5330993-A | Immunosuppressive compounds | VERTEX PHARMACEUTICALS, INC. (US) | 1994-07-19 | — | — | US | disclosed |