Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.48 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.43 |
| ▸ | IDH1 | O75874 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.35 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.35 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.35 |
| ▸ | TEK | Q02763 | 1/20 | 0.35 |
| ▸ | PDE2A | O00408 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3365903 | 0.86 | MAOA (0.40) | MAOB | |
| SCHEMBL28006547 | 0.81 | CALM1 (0.41) | CALM1IDH1MAOB | |
| SCHEMBL7996406 | 0.79 | CALM1 (0.40) | LTA4HCALM1IDH1PRSS1PRSS2 | |
| SCHEMBL458330 | 0.77 | PTGS2 (0.42) | — | |
| SCHEMBL3367670 | 0.76 | LOXL2 (0.43) | MAOB | |
| SCHEMBL2093039 | 0.76 | CALM1 (0.48) | LTA4HCALM1IDH1PRSS1PRSS2 | |
| SCHEMBL359220 | 0.76 | MAPT (0.38) | — | |
| SCHEMBL3948493 | 0.75 | MAOB (0.58) | MAOB | |
| SCHEMBL14605356 | 0.75 | NPC1 (0.60) | CA2 | |
| SCHEMBL1171484 | 0.74 | CNR1 (0.37) | CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106459358-B | Method for producing polyoxazolidone polymer compounds | 科思创德国股份有限公司 | 2020-05-15 | — | — | CN | disclosed |
| EP-3143065-B1 | METHOD FOR THE PRODUCTION OF POLYOXAZOLIDINONE POLYMER COMPOUNDS | COVESTRO DEUTSCHLAND AG (DE) | 2018-01-10 | — | — | EP | disclosed |
| US-20170081459-A1 | METHOD FOR THE PRODUCTION OF POLYOXAZOLIDINONE POLYMER COMPOUNDS | COVESTRO DEUTSCHLAND AG (DE) | 2017-03-23 | — | — | US | disclosed |
| EP-3143065-A1 | METHOD FOR THE PRODUCTION OF POLYOXAZOLIDINONE POLYMER COMPOUNDS | Covestro Deutschland AG (DE) | 2017-03-22 | — | — | EP | disclosed |
| CN-106459358-A | Method for the production of polyoxazolidinone polymer compounds | 科思创德国股份有限公司 | 2017-02-22 | — | — | CN | disclosed |
| WO-2015173101-A1 | METHOD FOR THE PRODUCTION OF POLYOXAZOLIDINONE POLYMER COMPOUNDS | COVESTRO DEUTSCHLAND AG (DE) | 2015-11-19 | — | — | WO | disclosed |
| US-5516797-A | SUPPRESSING GRAFT REJECTION | VERTEX PHARMACEUTICALS, INCORPORATED (US) | 1996-05-14 | — | — | US | disclosed |
| US-5330993-A | Immunosuppressive compounds | VERTEX PHARMACEUTICALS, INC. (US) | 1994-07-19 | — | — | US | disclosed |