Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.37 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.36 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.36 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.36 |
| ▸ | TUBB | P07437 | 1/20 | 0.36 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.36 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.36 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.36 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.36 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8939773 | 0.91 | KDM4E (0.41) | LTA4HPOLBSMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL8939787 | 0.88 | LTA4H (0.42) | LTA4HSMN1; SMN2ALDH1A1KDM4EHTT | |
| SCHEMBL6160386 | 0.85 | ABCB1 (0.44) | POLBSMN1; SMN2ABCB1ABCG2TUBB4A | |
| SCHEMBL8190525 | 0.85 | MEN1 (0.47) | SMN1; SMN2ALDH1A1KDM4EHTTABCB1 | |
| SCHEMBL8939758 | 0.84 | APP (0.41) | ALDH1A1GAATUBB4ATUBBTUBA3C | |
| SCHEMBL7746427 | 0.83 | HTR2A (0.42) | ABCB1ABCG2HPGD | |
| SCHEMBL7429582 | 0.83 | BCHE (0.40) | ABCB1ABCG2HPGD | |
| SCHEMBL6161069 | 0.82 | ALDH1A1 (0.42) | POLBSMN1; SMN2ALDH1A1KDM4EGAA | |
| SCHEMBL8939724 | 0.81 | MAOB (0.44) | POLBSMN1; SMN2ABCB1ABCG2TUBB4A | |
| SCHEMBL7746382 | 0.81 | TDP1 (0.40) | HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5516797-A | SUPPRESSING GRAFT REJECTION | VERTEX PHARMACEUTICALS, INCORPORATED (US) | 1996-05-14 | — | — | US | disclosed |