Benzoyl Peroxide

Benzoyl Peroxide

SCHEMBL8940146

O=C(O)C(Cl)Cl.O=C(O)c1ccccc1O.O=C(OOC(=O)c1ccccc1)c1ccccc1

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHE

The experimentally established mechanism targets of Benzoyl Peroxide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.56
HPGD P15428 5/20 0.56
KDM4E B2RXH2 3/20 0.56
SMN1; SMN2 Q16637 3/20 0.56
CA12 O43570 1/20 0.56
CA1 P00915 1/20 0.56
CA2 P00918 1/20 0.56
HMGB1 P09429 1/20 0.56
CA4 P22748 1/20 0.56
CA6 P23280 1/20 0.56
CA7 P43166 1/20 0.56
CA9 Q16790 1/20 0.56
NAPRT Q6XQN6 1/20 0.56
CA14 Q9ULX7 1/20 0.56
LMNA P02545 3/20 0.53
F2 P00734 1/20 0.53
HSD17B10 Q99714 4/20 0.47
ALOX15 P16050 3/20 0.44
ALOX12 P18054 1/20 0.43
TSHR P16473 4/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzoyl Peroxide SCHEMBL2873606 0.90 ALDH1A1 (0.69) ALDH1A1HPGDKDM4ESMN1; SMN2CA12
Salicylic Acid SCHEMBL28185563 0.79 ALDH1A1 (0.82) ALDH1A1HPGDKDM4ESMN1; SMN2CA12
Benzoyl Peroxide SCHEMBL30511565 0.79 F2 (0.77) ALDH1A1HPGDKDM4ESMN1; SMN2CA12
Benzoyl Peroxide SCHEMBL28111959 0.77 LMNA (0.81) ALDH1A1SMN1; SMN2NAPRTLMNAF2
Salicylic Acid SCHEMBL28186266 0.76 ALDH1A1 (0.75) ALDH1A1HPGDKDM4ESMN1; SMN2CA12
Salicylic Acid SCHEMBL6948351 0.75 HPGD (0.82) ALDH1A1HPGDKDM4ESMN1; SMN2CA12
Salicylic Acid SCHEMBL29483467 0.75 HPGD (0.82) ALDH1A1HPGDKDM4ESMN1; SMN2CA12
Salicylic Acid SCHEMBL3280603 0.75 ALDH1A1 (0.90) ALDH1A1HPGDKDM4ESMN1; SMN2CA12
Salicylic Acid SCHEMBL30403392 0.75 ALDH1A1 (0.90) ALDH1A1HPGDKDM4ESMN1; SMN2CA12
Salicylic Acid SCHEMBL1967 0.75 ALDH1A1 (1.00) ALDH1A1HPGDKDM4ESMN1; SMN2CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0679077-A4 NON-AQUEOUS LIQUID POWDER. SAFE & DRY CO INC (US) 1996-06-26 EP disclosed
EP-0679077-A1 NON-AQUEOUS LIQUID POWDER SAFE & DRY COMPANY, INC. (US) 1995-11-02 EP disclosed
WO-1994014403-A1 NON-AQUEOUS LIQUID POWDER SAFE & DRY COMPANY, INC. (US) 1994-07-07 WO disclosed