SCHEMBL8940312

SCHEMBL8940312

C=C(C)OCCOC(C)OS(=O)(=O)c1ccc(C)cc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.36
DHODH Q02127 1/20 0.35
KMT2A Q03164 3/20 0.35
MEN1 O00255 2/20 0.35
GAA P10253 4/20 0.35
ESR1 P03372 1/20 0.35
ESR2 Q92731 1/20 0.35
CYP2D6 P10635 1/20 0.33
CYP24A1 Q07973 1/20 0.33
GBA1 P04062 1/20 0.33
STAT3 P40763 1/20 0.32
CA2 P00918 2/20 0.32
VDR P11473 1/20 0.32
CA12 O43570 1/20 0.32
CA9 Q16790 1/20 0.32
TSHR P16473 1/20 0.32
CA1 P00915 1/20 0.32
MMP1 P03956 1/20 0.32
MMP2 P08253 1/20 0.32
MMP9 P14780 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8940480 0.96 ALDH1A1 (0.40) ALDH1A1DHODHKMT2AMEN1GAA
SCHEMBL10593963 0.82 ALDH1A1 (0.38) ALDH1A1DHODHKMT2AMEN1GAA
SCHEMBL361529 0.81 ALDH1A1 (0.43) ALDH1A1KMT2AMEN1GAAESR1
SCHEMBL15604373 0.79 ALDH1A1 (0.37) ALDH1A1DHODHKMT2AMEN1GAA
SCHEMBL17350537 0.79 AGER (0.39) ALDH1A1KMT2AMEN1GAAESR1
SCHEMBL21803209 0.79 GBA1 (0.40) ALDH1A1KMT2AMEN1GAAESR1
SCHEMBL28925139 0.78 ALDH1A1 (0.37) ALDH1A1DHODHKMT2AMEN1GAA
SCHEMBL7697577 0.78 ALDH1A1 (0.41) ALDH1A1KMT2AMEN1GAAESR1
SCHEMBL8940310 0.77 ALDH1A1 (0.35) ALDH1A1DHODHKMT2AMEN1GAA
SCHEMBL18301951 0.77 CA12 (0.41) ALDH1A1KMT2AGAAGBA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5563230-A POLYETHERSILOXANES NATIONAL SCIENCE COUNCIL (TW) 1996-10-08 US disclosed