Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | DHODH | Q02127 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP24A1 | Q07973 | 1/20 | 0.31 |
| ▸ | GBA1 | P04062 | 1/20 | 0.31 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.31 |
| ▸ | STAT3 | P40763 | 1/20 | 0.30 |
| ▸ | MMP2 | P08253 | 1/20 | 0.30 |
| ▸ | MMP9 | P14780 | 1/20 | 0.30 |
| ▸ | MMP8 | P22894 | 1/20 | 0.30 |
| ▸ | MMP13 | P45452 | 1/20 | 0.30 |
| ▸ | PSMD10 | O75832 | 1/20 | 0.30 |
| ▸ | VDR | P11473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8940312 | 0.96 | ALDH1A1 (0.36) | ALDH1A1DHODHGAAKMT2AMEN1 | |
| SCHEMBL7697577 | 0.83 | ALDH1A1 (0.41) | ALDH1A1GAAKMT2AMEN1ESR1 | |
| SCHEMBL15535742 | 0.82 | ALDH1A1 (0.40) | ALDH1A1GAAKMT2AMEN1ESR1 | |
| SCHEMBL8940478 | 0.81 | ALDH1A1 (0.38) | ALDH1A1DHODHGAAKMT2AMEN1 | |
| SCHEMBL8940310 | 0.80 | ALDH1A1 (0.35) | ALDH1A1DHODHGAAKMT2AMEN1 | |
| SCHEMBL10593963 | 0.79 | ALDH1A1 (0.38) | ALDH1A1DHODHGAAKMT2AMEN1 | |
| SCHEMBL361529 | 0.78 | ALDH1A1 (0.43) | ALDH1A1GAAKMT2AMEN1ESR1 | |
| SCHEMBL15604373 | 0.76 | ALDH1A1 (0.37) | ALDH1A1DHODHGAAKMT2AMEN1 | |
| SCHEMBL21803209 | 0.76 | GBA1 (0.40) | ALDH1A1GAAKMT2AMEN1ESR1 | |
| SCHEMBL17350537 | 0.76 | AGER (0.39) | ALDH1A1GAAKMT2AMEN1ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5563230-A | POLYETHERSILOXANES | NATIONAL SCIENCE COUNCIL (TW) | 1996-10-08 | — | — | US | disclosed |