Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | GBA1 | P04062 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 3/20 | 0.36 |
| ▸ | CA9 | Q16790 | 3/20 | 0.36 |
| ▸ | CA12 | O43570 | 2/20 | 0.36 |
| ▸ | CYP24A1 | Q07973 | 1/20 | 0.36 |
| ▸ | VDR | P11473 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7697577 | 0.96 | ALDH1A1 (0.41) | ALDH1A1LMNAHPGDHTTGAA | |
| SCHEMBL21803209 | 0.84 | GBA1 (0.40) | ALDH1A1GAAGBA1CYP3A4CYP2C9 | |
| SCHEMBL17350537 | 0.84 | AGER (0.39) | ALDH1A1LMNAHPGDHTTGAA | |
| SCHEMBL18301951 | 0.83 | CA12 (0.41) | ALDH1A1LMNAHPGDGAAGBA1 | |
| SCHEMBL15535742 | 0.82 | ALDH1A1 (0.40) | ALDH1A1LMNAHPGDGAAGBA1 | |
| SCHEMBL244713 | 0.82 | CA2 (0.41) | ALDH1A1LMNAHPGDGAAGBA1 | |
| SCHEMBL15604373 | 0.82 | ALDH1A1 (0.37) | ALDH1A1GAAGBA1CYP3A4CYP2C9 | |
| SCHEMBL8940312 | 0.81 | ALDH1A1 (0.36) | ALDH1A1GAAGBA1CYP3A4CYP2C9 | |
| SCHEMBL890642 | 0.81 | GAA (0.50) | ALDH1A1LMNAHTTGAAMAPT | |
| SCHEMBL28925139 | 0.81 | ALDH1A1 (0.37) | ALDH1A1HPGDGAAGBA1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11094964-B2 | Rechargeable electrochemical cell | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) | 2021-08-17 | — | — | US | disclosed |
| US-10750746-B2 | Structure, synthesis, and applications for poly (phenylene) ethynylenes (PPEs) | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2020-08-25 | — | — | US | disclosed |
| EP-3545580-A2 | RECHARGEABLE ELECTROCHEMICAL CELL | Board of Trustees of Michigan State University (US) | 2019-10-02 | — | — | EP | disclosed |
| US-10336743-B2 | Aminopyrimidine kinase inhibitors | Jasco Pharmaceuticals, LLC (US) | 2019-07-02 | — | — | US | disclosed |
| US-20190116797-A1 | STRUCTURE, SYNTHESIS, AND APPLICATIONS FOR POLY(PHENYLENE ETHYNYLENES) (PPEs) | UNIV FLORIDA (US) | 2019-04-25 | — | — | US | disclosed |
| US-10174042-B2 | Structure, synthesis, and applications for poly (phenylene) ethynylenes (PPEs) | STC.UNM (US) | 2019-01-08 | — | — | US | disclosed |
| US-20170247367-A1 | AMINOPYRIMIDINE KINASE INHIBITORS | P2K DYNAMICS INC. | 2017-08-31 | — | — | US | disclosed |
| US-9629840-B2 | Aminopyrimidine kinase inhibitors | Jasco Pharmaceuticals, LLC (US) | 2017-04-25 | — | — | US | disclosed |
| US-20170057970-A1 | STRUCTURE, SYNTHESIS, AND APPLICATIONS FOR POLY (PHENYLENE) ETHYNYLENES (PPEs) | WHITTEN DAVID G (US) | 2017-03-02 | — | — | US | disclosed |
| US-9527806-B2 | Structure, synthesis, and applications for poly (phenylene) ethynylenes (PPEs) | STC.UNM (US) | 2016-12-27 | — | — | US | disclosed |
| US-20150202205-A1 | AMINOPYRIMIDINE KINASE INHIBITORS | P2K DYNAMICS INC. | 2015-07-23 | — | — | US | disclosed |
| US-8927525-B2 | Aminopyrimidine kinase inhibitors | Jasco Pharmaceuticals, LLC (US) | 2015-01-06 | — | — | US | disclosed |
| EP-2776432-A1 | AMINOPYRIMIDINE KINASE INHIBITORS | Jasco Pharmaceuticals LLC (US) | 2014-09-17 | — | — | EP | disclosed |
| US-20130310342-A1 | Aminopyrimidine Kinase Inhibitors | P2K DYNAMICS INC. | 2013-11-21 | — | — | US | disclosed |
| US-20130210828-A1 | STRUCTURE, SYNTHESIS, AND APPLICATIONS FOR POLY (PHENYLENE) ETHYNYLENES (PPEs) | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. | 2013-08-15 | — | — | US | disclosed |
| WO-2013066684-A1 | AMINOPYRIMIDINE KINASE INHIBITORS | Jasco Pharmaceuticals, LLC (US) | 2013-05-10 | — | — | WO | disclosed |
| WO-2012009484-A2 | STRUCTURE, SYNTHESIS, AND APPLICATIONS FOR POLY (PHENYLENE) ETHYNYLENES (PPES) | STC.UNM (US) | 2012-01-19 | — | — | WO | disclosed |
| US-4436664-A | PHASE TRANSFER AGENTS | W. R. GRACE & CO. (US) | 1984-03-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170247367-A1 | AMINOPYRIMIDINE KINASE INHIBITORS | PIM1, PIM2, PIM3 | ALDH1A1 3087/4885LMNA 3264/4885HPGD 3594/4885 |
| US-10174042-B2 | Structure, synthesis, and applications for poly (phenylene) ethynylenes (PPEs) | PGLS, POLI, PARN | ALDH1A1 3189/4885LMNA 1725/4885HPGD 3704/4885 |
| US-20130310342-A1 | Aminopyrimidine Kinase Inhibitors | PIM1, PIM2, PIM3 | ALDH1A1 2942/4885LMNA 3639/4885HPGD 3472/4885 |
| US-20130210828-A1 | STRUCTURE, SYNTHESIS, AND APPLICATIONS FOR POLY (PHENYLENE) ETHYNYLENES (PPEs) | PGLS, POLI, PARN | ALDH1A1 3189/4885LMNA 1725/4885HPGD 3704/4885 |
| US-11094964-B2 | Rechargeable electrochemical cell | NES, SLC25A13, HCN2 | ALDH1A1 2472/4885LMNA 2239/4885HPGD 2971/4885 |
| US-20190116797-A1 | STRUCTURE, SYNTHESIS, AND APPLICATIONS FOR POLY(PHENYLENE ETHYNYLENES) (PPEs) | PGLS, POLI, PARN | ALDH1A1 3195/4885LMNA 1763/4885HPGD 3655/4885 |
| US-20170057970-A1 | STRUCTURE, SYNTHESIS, AND APPLICATIONS FOR POLY (PHENYLENE) ETHYNYLENES (PPEs) | PGLS, POLI, PARN | ALDH1A1 3189/4885LMNA 1725/4885HPGD 3704/4885 |
| US-20150202205-A1 | AMINOPYRIMIDINE KINASE INHIBITORS | PIM1, PIM2, PIM3 | ALDH1A1 2942/4885LMNA 3639/4885HPGD 3472/4885 |
| US-10336743-B2 | Aminopyrimidine kinase inhibitors | PIM1, PIM2, PIM3 | ALDH1A1 2942/4885LMNA 3639/4885HPGD 3472/4885 |
| US-10750746-B2 | Structure, synthesis, and applications for poly (phenylene) ethynylenes (PPEs) | PGLS, POLI, PARN | ALDH1A1 3189/4885LMNA 1725/4885HPGD 3704/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.