Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 2/20 | 0.34 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.34 |
| ▸ | PDE2A | O00408 | 4/20 | 0.32 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.32 |
| ▸ | TEAD1 | P28347 | 3/20 | 0.31 |
| ▸ | CCR1 | P32246 | 1/20 | 0.31 |
| ▸ | CCR2 | P41597 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | TDO2 | P48775 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.30 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27654897 | 0.61 | CES2 (0.50) | KDM4EALDH1A1HSD11B1 | |
| SCHEMBL7329291 | 0.61 | ELANE (0.47) | ELANEKDM4EALDH1A1POLB | |
| SCHEMBL27674822 | 0.60 | GSK3B (0.47) | KDM4EALDH1A1 | |
| SCHEMBL1347245 | 0.59 | CES2 (0.38) | TEAD1HSD11B1 | |
| SCHEMBL867225 | 0.58 | FFAR1 (0.45) | — | |
| SCHEMBL29019486 | 0.56 | ALDH1A1 (0.42) | KDM4EALDH1A1 | |
| SCHEMBL9280969 | 0.56 | GSK3B (0.52) | PDE2A | |
| SCHEMBL7347918 | 0.54 | SLC6A3 (0.33) | ELANEPOLB | |
| SCHEMBL27614635 | 0.54 | TRPV1 (0.51) | KDM4EALDH1A1 | |
| SCHEMBL23182220 | 0.54 | CES2 (0.50) | PDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5489604-A | TREATING DEGENERATIVE DISEASES | STERLING WINTHROP, INC. (US) | 1996-02-06 | — | — | US | disclosed |