Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 2/20 | 0.45 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.45 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.45 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.43 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.43 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.43 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.40 |
| ▸ | FABP4 | P15090 | 3/20 | 0.40 |
| ▸ | FABP5 | Q01469 | 3/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13794224 | 0.74 | TP53 (0.49) | HTR1AADRA1DADRA1AADRA1BMRGPRX4 | |
| SCHEMBL78713 | 0.71 | CA12 (0.50) | P2RX7TP53CYP3A4TSHRALDH1A1 | |
| SCHEMBL30772335 | 0.71 | CA12 (0.50) | P2RX7TP53CYP3A4TSHRALDH1A1 | |
| SCHEMBL2558213 | 0.71 | ENPP2 (0.50) | HTR1AADRA1DADRA1AADRA1BMRGPRX4 | |
| SCHEMBL12894383 | 0.71 | CARM1 (0.45) | HTR1AADRA1DADRA1AADRA1BMRGPRX4 | |
| SCHEMBL9819251 | 0.71 | ALDH1A1 (0.46) | MRGPRX4TP53CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL30139648 | 0.71 | PNMT (0.47) | TSHRALDH1A1SMN1; SMN2IDO1 | |
| SCHEMBL1547751 | 0.70 | L3MBTL1 (0.54) | MRGPRX4P2RX7TP53CYP1A2CYP3A4 | |
| Fluoride SCHEMBL28106604 | 0.69 | CA12 (0.48) | P2RX7TP53CYP3A4TSHRALDH1A1 | |
| SCHEMBL22402260 | 0.68 | MRGPRX4 (0.45) | MRGPRX4FABP4FABP5CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0700384-A1 | PROCESS FOR PREPARING AND RESOLVING 2-PHENYL-3-AMINOPIPERIDINE | PFIZER (US) | 1996-03-13 | — | — | EP | disclosed |
| WO-1994027966-A1 | PROCESS FOR PREPARING AND RESOLVING 2-PHENYL-3-AMINOPIPERIDINE | PFIZER INC. (US) | 1994-12-08 | — | — | WO | disclosed |