Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 2/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.41 |
| ▸ | CETP | P11597 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | JAK1 | P23458 | 1/20 | 0.36 |
| ▸ | TYK2 | P29597 | 1/20 | 0.36 |
| ▸ | JAK3 | P52333 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13111719 | 0.86 | CA2 (0.50) | CA2PTGS2LMNAMAPK1SMN1; SMN2 | |
| SCHEMBL8940769 | 0.86 | HTR7 (0.53) | HTR7GABRA1GABRB2CETPCA2 | |
| SCHEMBL8189614 | 0.80 | PDE4A (0.42) | CA2PTGS2LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL15693312 | 0.77 | ALDH1A1 (0.42) | LMNASMN1; SMN2ALDH1A1MAPTKMT2A | |
| SCHEMBL12967349 | 0.77 | CACNA1H (0.39) | — | |
| SCHEMBL26023236 | 0.76 | CYP1A2 (0.41) | SMN1; SMN2NPC1ALDH1A1MAPTRAB9A | |
| SCHEMBL10274466 | 0.76 | CSNK2A1 (0.51) | LMNASMN1; SMN2NPC1ALDH1A1MAPT | |
| SCHEMBL12845586 | 0.75 | CSNK2A1 (0.42) | SMN1; SMN2KMT2APDE4APDE4BPDE4C | |
| SCHEMBL12845579 | 0.75 | CSNK2A1 (0.42) | SMN1; SMN2KMT2APDE4APDE4BPDE4C | |
| SCHEMBL8171104 | 0.74 | KCNH2 (0.41) | LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0700384-A1 | PROCESS FOR PREPARING AND RESOLVING 2-PHENYL-3-AMINOPIPERIDINE | PFIZER (US) | 1996-03-13 | — | — | EP | disclosed |
| WO-1994027966-A1 | PROCESS FOR PREPARING AND RESOLVING 2-PHENYL-3-AMINOPIPERIDINE | PFIZER INC. (US) | 1994-12-08 | — | — | WO | disclosed |