Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 4/20 | 0.53 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.50 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.50 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | CETP | P11597 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22215972 | 0.86 | GABRA1 (0.72) | GABRA1GABRB2GAAALDH1A1LMNA | |
| SCHEMBL8940640 | 0.86 | HTR7 (0.43) | HTR7GABRA1GABRB2CA2PTGS2 | |
| SCHEMBL5991474 | 0.85 | HTR7 (0.49) | HTR7GABRA1GABRB2ALDH1A1LMNA | |
| SCHEMBL31428 | 0.84 | CA2 (0.71) | CA2PTGS2ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL31275634 | 0.84 | CA2 (0.71) | CA2PTGS2ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL9199186 | 0.83 | SYK (0.47) | GABRA1GABRB2TUBB1GAAALDH1A1 | |
| SCHEMBL15055469 | 0.83 | GABRA1 (0.58) | HTR7GABRA1GABRB2CA2KDM4E | |
| Water SCHEMBL8587595 | 0.82 | CA2 (0.68) | CA2PTGS2ALDH1A1LMNASMN1; SMN2 | |
| Ammonia Solution, Strong SCHEMBL266403 | 0.82 | CA2 (0.68) | CA2PTGS2ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL22130621 | 0.82 | MGAM (0.49) | GABRA1GABRB2GAAALOX5CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0700384-A1 | PROCESS FOR PREPARING AND RESOLVING 2-PHENYL-3-AMINOPIPERIDINE | PFIZER (US) | 1996-03-13 | — | — | EP | disclosed |
| WO-1994027966-A1 | PROCESS FOR PREPARING AND RESOLVING 2-PHENYL-3-AMINOPIPERIDINE | PFIZER INC. (US) | 1994-12-08 | — | — | WO | disclosed |