Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 2/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.50 |
| ▸ | LTA4H | P09960 | 2/20 | 0.48 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.47 |
| ▸ | TUBB | P07437 | 1/20 | 0.47 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.47 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.47 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.47 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.47 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.47 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.47 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.47 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.47 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.47 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.47 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.47 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.47 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.47 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8864080 | 0.83 | LTA4H (0.55) | LTA4HTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL11646840 | 0.77 | LTA4H (0.61) | LTA4HTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL27613014 | 0.77 | ALDH1A1 (0.55) | HDAC4HDAC2HDAC8GABRA1GABRB2 | |
| SCHEMBL8940685 | 0.77 | ALDH1A1 (0.55) | HDAC4HDAC2HDAC8GABRA1GABRB2 | |
| SCHEMBL9379302 | 0.77 | FYN (0.52) | GABRA1GABRB2ALDH1A1GAAMAPT | |
| SCHEMBL2099937 | 0.75 | ALDH1A1 (0.63) | LTA4HTUBB4ATUBBTUBA3CTUBA1B | |
| Methoxymethane SCHEMBL11646837 | 0.75 | LTA4H (0.59) | LTA4HTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL6572244 | 0.74 | NPC1 (0.53) | HDAC4HDAC2HDAC8GABRA1GABRB2 | |
| SCHEMBL1911833 | 0.74 | LTA4H (0.57) | LTA4HALDH1A1TTRERN1KDM4E | |
| SCHEMBL4958922 | 0.73 | TTR (0.65) | LTA4HTUBB4ATUBBTUBA3CTUBA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0700384-A1 | PROCESS FOR PREPARING AND RESOLVING 2-PHENYL-3-AMINOPIPERIDINE | PFIZER (US) | 1996-03-13 | — | — | EP | disclosed |
| WO-1994027966-A1 | PROCESS FOR PREPARING AND RESOLVING 2-PHENYL-3-AMINOPIPERIDINE | PFIZER INC. (US) | 1994-12-08 | — | — | WO | disclosed |