Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOAT2 | O75908 | 1/20 | 0.42 |
| ▸ | MYC | P01106 | 1/20 | 0.42 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.42 |
| ▸ | MAP2K3 | P46734 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | FPR1 | P21462 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.40 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.40 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.40 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.40 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.40 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8941153 | 0.79 | SOAT2 (0.38) | SOAT2MYCSOAT1MAP2K3MEN1 | |
| SCHEMBL8941282 | 0.78 | SOAT2 (0.46) | SOAT2MYCSOAT1MAP2K3 | |
| SCHEMBL8941429 | 0.77 | HSP90AA1 (0.44) | ALDH1A1MEN1KMT2AHSP90AA1HSP90AB1 | |
| SCHEMBL9059390 | 0.76 | SOAT2 (0.36) | SOAT2MYCSOAT1MAP2K3MEN1 | |
| SCHEMBL8941260 | 0.75 | SOAT2 (0.48) | SOAT2MYCSOAT1MAP2K3ALDH1A1 | |
| SCHEMBL8941381 | 0.71 | SOAT1 (0.55) | SOAT2MYCSOAT1MAP2K3ALDH1A1 | |
| SCHEMBL8941146 | 0.69 | SOAT2 (0.47) | SOAT2MYCSOAT1MAP2K3 | |
| SCHEMBL14015388 | 0.66 | FABP4 (0.58) | SOAT2MYCSOAT1MAP2K3 | |
| SCHEMBL27562021 | 0.65 | PTGES2 (0.41) | SOAT2MYCSOAT1MAP2K3MEN1 | |
| SCHEMBL8941187 | 0.65 | TSHR (0.48) | SOAT2MYCSOAT1MAP2K3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996019444-A1 | SULFONATE ACAT INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1996-06-27 | — | — | WO | claimed |
| WO-1996019444-A1 | SULFONATE ACAT INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1996-06-27 | — | — | WO | disclosed |
| US-5510379-A | USEFUL FOR TREATING HYPERCHOLESTEROLEMIA AND ATHEROSCLEROSIS | WARNER-LAMBERT COMPANY (US) | 1996-04-23 | — | — | US | disclosed |