Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOAT2 | O75908 | 1/20 | 0.48 |
| ▸ | MYC | P01106 | 1/20 | 0.48 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.48 |
| ▸ | MAP2K3 | P46734 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MDM4 | O15151 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8941187 | 0.90 | TSHR (0.48) | SOAT2MYCSOAT1MAP2K3TSHR | |
| SCHEMBL8941381 | 0.80 | SOAT1 (0.55) | SOAT2MYCSOAT1MAP2K3KMT2A | |
| SCHEMBL8941282 | 0.79 | SOAT2 (0.46) | SOAT2MYCSOAT1MAP2K3 | |
| SCHEMBL8941259 | 0.75 | SOAT2 (0.42) | SOAT2MYCSOAT1MAP2K3KMT2A | |
| SCHEMBL8962577 | 0.72 | TSHR (0.46) | SOAT2SOAT1TSHRKMT2AMEN1 | |
| SCHEMBL8941392 | 0.69 | SMN1; SMN2 (0.56) | SOAT2MYCSOAT1MAP2K3KMT2A | |
| SCHEMBL8941146 | 0.69 | SOAT2 (0.47) | SOAT2MYCSOAT1MAP2K3 | |
| SCHEMBL8121753 | 0.69 | TSHR (0.55) | TSHRKMT2AMEN1MAPTMDM4 | |
| SCHEMBL28812298 | 0.68 | SOAT2 (0.43) | SOAT2MYCSOAT1MAP2K3ALDH1A1 | |
| SCHEMBL14015388 | 0.67 | FABP4 (0.58) | SOAT2MYCSOAT1MAP2K3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996019444-A1 | SULFONATE ACAT INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1996-06-27 | — | — | WO | claimed |
| WO-1996019444-A1 | SULFONATE ACAT INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1996-06-27 | — | — | WO | disclosed |
| US-5510379-A | USEFUL FOR TREATING HYPERCHOLESTEROLEMIA AND ATHEROSCLEROSIS | WARNER-LAMBERT COMPANY (US) | 1996-04-23 | — | — | US | disclosed |