Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.44 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.44 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.44 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.44 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | ENPP3 | O14638 | 2/20 | 0.43 |
| ▸ | ENPP1 | P22413 | 2/20 | 0.43 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.41 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.41 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.41 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.41 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.41 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.41 |
| ▸ | FABP3 | P05413 | 1/20 | 0.40 |
| ▸ | FABP4 | P15090 | 1/20 | 0.40 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8941259 | 0.77 | SOAT2 (0.42) | HSP90AA1HSP90AB1PDK1PDK2PDK3 | |
| SCHEMBL8941150 | 0.76 | FABP3 (0.36) | ALDH1A1ENPP3ENPP1PSEN1PSEN2 | |
| SCHEMBL9059388 | 0.75 | ENPP3 (0.39) | ENPP3ENPP1PSEN1PSEN2APH1B | |
| SCHEMBL11888501 | 0.72 | FABP4 (0.55) | ALDH1A1ENPP3ENPP1PSEN1PSEN2 | |
| SCHEMBL8941378 | 0.71 | SMN1; SMN2 (0.50) | ALDH1A1ENPP3ENPP1MEN1KMT2A | |
| SCHEMBL15082971 | 0.71 | FABP3 (0.44) | ALDH1A1ENPP3ENPP1PSEN1PSEN2 | |
| SCHEMBL15082953 | 0.70 | FABP3 (0.43) | ENPP3ENPP1PSEN1PSEN2APH1B | |
| SCHEMBL90032 | 0.70 | ALDH1A1 (0.58) | HSP90AA1HSP90AB1PDK1PDK2PDK3 | |
| SCHEMBL14838301 | 0.68 | FABP4 (0.41) | ENPP3ENPP1PSEN1PSEN2APH1B | |
| SCHEMBL15184276 | 0.68 | PSEN1 (0.41) | ALDH1A1ENPP3ENPP1PSEN1PSEN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996019444-A1 | SULFONATE ACAT INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1996-06-27 | — | — | WO | disclosed |
| US-5510379-A | USEFUL FOR TREATING HYPERCHOLESTEROLEMIA AND ATHEROSCLEROSIS | WARNER-LAMBERT COMPANY (US) | 1996-04-23 | — | — | US | disclosed |