SCHEMBL894129

SCHEMBL894129

C=CP(=O)(C=C)c1ccccc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.60
ALOX15 P16050 1/20 0.60
CA2 P00918 1/20 0.46
CA4 P22748 1/20 0.46
CA5A P35218 1/20 0.46
CFTR P13569 1/20 0.41
ALDH1A1 P00352 5/20 0.39
GAA P10253 2/20 0.39
L3MBTL1 Q9Y468 2/20 0.39
NPSR1 Q6W5P4 2/20 0.39
TDP1 Q9NUW8 1/20 0.39
MAPT P10636 1/20 0.39
ALPG P10696 1/20 0.39
ALOX12 P18054 1/20 0.39
NPY1R P25929 1/20 0.39
HTT P42858 1/20 0.39
NPY2R P49146 1/20 0.39
USP2 O75604 1/20 0.38
ESR1 P03372 1/20 0.38
PKM P14618 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2735743 0.87 ALOX15 (0.48) TSHRALOX15CA2CA4CA5A
SCHEMBL2735742 0.79 ALOX15 (0.38) TSHRALOX15
SCHEMBL1051430 0.79 TSHR (0.60) TSHRALOX15CA2CA4CA5A
SCHEMBL29197891 0.76 CA2 (0.48) TSHRALOX15CA2CA4CA5A
SCHEMBL23732406 0.75 CYP2A6 (0.38) TSHRALOX15ALDH1A1SMN1; SMN2LMNA
SCHEMBL14198443 0.75 TSHR (0.56) TSHRALOX15CA2CA4CA5A
SCHEMBL10598923 0.75 TSHR (1.00) TSHRALOX15CA2CA4CA5A
SCHEMBL10347956 0.75 TSHR (0.56) TSHRALOX15CA2CA4CA5A
SCHEMBL893399 0.75 TGM2 (0.36) TSHRALOX15CA2SMN1; SMN2
SCHEMBL8137563 0.75 TSHR (0.56) TSHRALOX15CA2CA4CA5A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3747942-A1 BRIDGED PHOSPHORUS BASED FLAME RETARDANTS EMPA Eidgenössische Materialprüfungs- und Forschungsanstalt (CH) 2020-12-09 EP claimed
US-20250197568-A1 PHOSPHORUS CONTAINING OLIGOMERS AND POLYMERS EMPA EIDGENOESSISCHE MATERIALPRUEFUNGS- UND FORSCHUNGSANSTALT (CH) 2025-06-19 US disclosed
US-12071514-B2 Phosphorus containing oligomers and polymers EMPA EIDGENOESSISCHE MATERIALPRUEFUNGS- UND FORSCHUNGSANSTALT (CH) 2024-08-27 US disclosed
EP-3794061-B1 PHOSPHORUS CONTAINING OLIGOMERS AND POLYMERS EMPA EIDGENOESSISCHE MAT & FORSCHUNGSANSTALT (CH) 2023-07-05 EP disclosed
EP-3794061-B1 PHOSPHORUS CONTAINING OLIGOMERS AND POLYMERS EMPA EIDGENOESSISCHE MAT & FORSCHUNGSANSTALT (CH) 2023-07-05 EP disclosed
US-20210371591-A1 PHOSPHORUS CONTAINING OLIGOMERS AND POLYMERS EMPA EIDGENOESSISCHE MATERIALPRUEFUNGS- UND FORSCHUNGSANSTALT (CH) 2021-12-02 US disclosed
US-20210371591-A1 PHOSPHORUS CONTAINING OLIGOMERS AND POLYMERS EMPA EIDGENOESSISCHE MATERIALPRUEFUNGS- UND FORSCHUNGSANSTALT (CH) 2021-12-02 US disclosed
WO-2020245434-A1 BRIDGED PHOSPHORUS-BASED FLAME RETARDANTS EMPA EIDGENÖSSISCHE MATERIALPRÜFUNGS- UND FORSCHUNGSANSTALT (CH) 2020-12-10 WO disclosed
WO-2020245434-A1 BRIDGED PHOSPHORUS-BASED FLAME RETARDANTS EMPA EIDGENÖSSISCHE MATERIALPRÜFUNGS- UND FORSCHUNGSANSTALT (CH) 2020-12-10 WO disclosed
EP-3747942-A1 BRIDGED PHOSPHORUS BASED FLAME RETARDANTS EMPA Eidgenössische Materialprüfungs- und Forschungsanstalt (CH) 2020-12-09 EP disclosed
WO-2008090570-A1 NOVEL ANTIMICROBIALS PANACEA BIOTEC LTD (IN) 2008-07-31 WO disclosed
US-20080039426-A1 INHIBITORS OF TYROSINE KINASES AND USES THEREOF PHARMACYCLICS, INC. (US) 2008-02-14 US disclosed
US-20080039426-A1 INHIBITORS OF TYROSINE KINASES AND USES THEREOF PHARMACYCLICS, INC. (US) 2008-02-14 US disclosed
US-20080039426-A1 INHIBITORS OF TYROSINE KINASES AND USES THEREOF PHARMACYCLICS, INC. (US) 2008-02-14 US disclosed
WO-2008010985-A2 PHOSPHORUS DERIVATIVES AS HISTONE DEACETYLASE INHIBITORS MERCK & CO., INC. (US) 2008-01-24 WO disclosed
WO-2008010985-A2 PHOSPHORUS DERIVATIVES AS HISTONE DEACETYLASE INHIBITORS MERCK & CO., INC. (US) 2008-01-24 WO disclosed
WO-2007087068-A2 INHIBITORS OF TYROSINE KINASES AND USES THEREOF PHARMACYCLICS, INC. (US) 2007-08-02 WO disclosed
WO-2007087068-A2 INHIBITORS OF TYROSINE KINASES AND USES THEREOF PHARMACYCLICS, INC. (US) 2007-08-02 WO disclosed
WO-2006024862-A2 DESYMMETRISATION PROCESS FOR THE PREPARATION OF CHIRAL PHOSPHINES ISIS INNOVATION LIMITED (GB) 2006-03-09 WO disclosed
US-3931196-A Phosphinolines and phosphindolines MONASH UNIVERSITY (AU) 1976-01-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250197568-A1 PHOSPHORUS CONTAINING OLIGOMERS AND POLYMERS PHOSPHO1, PPIP5K2, PNKP TSHR 4284/4885ALOX15 240/4885CA2 2665/4885
US-12071514-B2 Phosphorus containing oligomers and polymers PHOSPHO1, PPIP5K2, PNKP TSHR 4284/4885ALOX15 240/4885CA2 2665/4885
US-20210371591-A1 PHOSPHORUS CONTAINING OLIGOMERS AND POLYMERS PHOSPHO1, PPIP5K2, PNKP TSHR 4284/4885ALOX15 240/4885CA2 2665/4885
US-20080039426-A1 INHIBITORS OF TYROSINE KINASES AND USES THEREOF LCK, ABL1, SRC TSHR 2700/4885ALOX15 3581/4885CA2 3931/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.