Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | ENPP3 | O14638 | 2/20 | 0.47 |
| ▸ | ENPP1 | P22413 | 2/20 | 0.47 |
| ▸ | SOAT2 | O75908 | 2/20 | 0.46 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.46 |
| ▸ | MYC | P01106 | 1/20 | 0.46 |
| ▸ | MAP2K3 | P46734 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8941381 | 0.76 | SOAT1 (0.55) | SMN1; SMN2SOAT2SOAT1MYCMAP2K3 | |
| SCHEMBL8941450 | 0.72 | SMN1; SMN2 (0.49) | SMN1; SMN2SOAT2SOAT1KMT2AMEN1 | |
| SCHEMBL9843936 | 0.72 | SMN1; SMN2 (0.77) | SMN1; SMN2SOAT2SOAT1KMT2AMEN1 | |
| SCHEMBL9463623 | 0.72 | SMN1; SMN2 (0.62) | SMN1; SMN2SOAT2SOAT1KMT2AMEN1 | |
| SCHEMBL8941429 | 0.71 | HSP90AA1 (0.44) | SMN1; SMN2ENPP3ENPP1KMT2AMEN1 | |
| SCHEMBL11888501 | 0.71 | FABP4 (0.55) | ENPP3ENPP1SOAT2SOAT1MYC | |
| SCHEMBL9463263 | 0.71 | SMN1; SMN2 (0.60) | SMN1; SMN2SOAT2SOAT1KMT2AMEN1 | |
| SCHEMBL28229524 | 0.69 | SMN1; SMN2 (0.72) | SMN1; SMN2SOAT2SOAT1KMT2AMEN1 | |
| SCHEMBL9463095 | 0.69 | SMN1; SMN2 (0.72) | SMN1; SMN2SOAT2SOAT1KMT2AMEN1 | |
| SCHEMBL17639907 | 0.69 | FABP4 (0.57) | ENPP3ENPP1SOAT2SOAT1MYC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5510379-A | USEFUL FOR TREATING HYPERCHOLESTEROLEMIA AND ATHEROSCLEROSIS | WARNER-LAMBERT COMPANY (US) | 1996-04-23 | — | — | US | claimed |