Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 13/20 | 0.63 |
| ▸ | ACACB | O00763 | 1/20 | 0.44 |
| ▸ | ACACA | Q13085 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 5/20 | 0.42 |
| ▸ | PPARA | Q07869 | 3/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 7/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8941747 | 0.90 | ALOX5 (0.53) | ALOX5PPARGPPARAEPHX2 | |
| SCHEMBL8941426 | 0.84 | ALOX5 (0.54) | ALOX5PPARGPPARAEPHX2 | |
| SCHEMBL8941404 | 0.82 | ALOX5 (0.54) | ALOX5PPARGPPARAEPHX2 | |
| SCHEMBL8941581 | 0.82 | PPARG (0.49) | ALOX5PPARGPPARAEPHX2 | |
| SCHEMBL9046388 | 0.79 | ALOX5 (1.00) | ALOX5ACACBACACAEPHX2 | |
| SCHEMBL8941751 | 0.77 | ALOX5 (0.53) | ALOX5LMNACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL8941436 | 0.74 | PPARG (0.47) | ALOX5PPARGPPARAEPHX2 | |
| SCHEMBL4730488 | 0.73 | ALOX5 (0.54) | ALOX5EPHX2 | |
| SCHEMBL9047950 | 0.73 | ALOX5 (0.83) | ALOX5ACACBACACAEPHX2LMNA | |
| SCHEMBL8941375 | 0.73 | ALOX5 (0.46) | ALOX5PPARGPPARAEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5552424-A | Isoxazolines as antiinflammatory agents | PFIZER INC. (US) | 1996-09-03 | — | — | US | disclosed |