Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 10/20 | 0.47 |
| ▸ | PPARA | Q07869 | 8/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 3/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8941581 | 0.90 | PPARG (0.49) | PPARGPPARAALOX5EPHX2 | |
| SCHEMBL8941589 | 0.82 | PPARG (0.49) | PPARGPPARAALOX5EPHX2 | |
| SCHEMBL8941747 | 0.81 | ALOX5 (0.53) | PPARGPPARAALOX5EPHX2 | |
| SCHEMBL8941404 | 0.81 | ALOX5 (0.54) | PPARGPPARAALOX5EPHX2 | |
| SCHEMBL8941364 | 0.75 | PPARG (0.47) | PPARGPPARAALOX5CA1CA2 | |
| SCHEMBL8941351 | 0.75 | PPARG (0.48) | PPARGPPARA | |
| SCHEMBL8941419 | 0.74 | ALOX5 (0.63) | PPARGPPARAALOX5EPHX2 | |
| SCHEMBL9047354 | 0.72 | ALOX5 (0.43) | ALOX5EPHX2 | |
| SCHEMBL8941426 | 0.72 | ALOX5 (0.54) | PPARGPPARAALOX5EPHX2 | |
| SCHEMBL8941375 | 0.69 | ALOX5 (0.46) | PPARGPPARAALOX5EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5552424-A | Isoxazolines as antiinflammatory agents | PFIZER INC. (US) | 1996-09-03 | — | — | US | disclosed |