Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 19/20 | 0.54 |
| ▸ | EPHX2 | P34913 | 11/20 | 0.48 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8941404 | 0.91 | ALOX5 (0.54) | ALOX5EPHX2PPARGPPARA | |
| SCHEMBL8941375 | 0.89 | ALOX5 (0.46) | ALOX5EPHX2PPARGPPARA | |
| SCHEMBL8941747 | 0.86 | ALOX5 (0.53) | ALOX5EPHX2PPARGPPARA | |
| SCHEMBL8941419 | 0.84 | ALOX5 (0.63) | ALOX5EPHX2PPARGPPARA | |
| SCHEMBL8941462 | 0.82 | PPARG (0.44) | ALOX5PPARGPPARA | |
| SCHEMBL8941581 | 0.82 | PPARG (0.49) | ALOX5EPHX2PPARGPPARA | |
| SCHEMBL8941411 | 0.82 | PPARG (0.43) | ALOX5EPHX2PPARGPPARA | |
| SCHEMBL8941475 | 0.81 | PPARG (0.41) | PPARGPPARA | |
| SCHEMBL8941431 | 0.81 | PPARG (0.39) | ALOX5PPARGPPARA | |
| SCHEMBL8941580 | 0.81 | ALOX5 (0.46) | ALOX5EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5552424-A | Isoxazolines as antiinflammatory agents | PFIZER INC. (US) | 1996-09-03 | — | — | US | disclosed |