Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 5/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.68 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.54 |
| ▸ | HTR6 | P50406 | 1/20 | 0.54 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 4/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.49 |
| ▸ | PGR | P06401 | 2/20 | 0.49 |
| ▸ | MMP2 | P08253 | 2/20 | 0.46 |
| ▸ | MMP9 | P14780 | 2/20 | 0.46 |
| ▸ | MMP8 | P22894 | 2/20 | 0.46 |
| ▸ | MMP12 | P39900 | 2/20 | 0.46 |
| ▸ | MMP13 | P45452 | 2/20 | 0.46 |
| ▸ | MMP14 | P50281 | 2/20 | 0.46 |
| ▸ | MMP16 | P51512 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MMP3 | P08254 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17287077 | 1.00 | HTT (0.68) | HTTSMN1; SMN2PTGS2HTR6SOS1 | |
| SCHEMBL7359540 | 0.90 | SOS1 (0.64) | HTTSMN1; SMN2PTGS2SOS1LMNA | |
| SCHEMBL6848913 | 0.90 | HTT (0.74) | HTTSMN1; SMN2HTR6SOS1LMNA | |
| SCHEMBL9323430 | 0.88 | HTT (0.78) | HTTSMN1; SMN2HTR6SOS1LMNA | |
| SCHEMBL17936671 | 0.88 | HTR6 (0.70) | HTTSMN1; SMN2PTGS2HTR6ALDH1A1 | |
| SCHEMBL7655181 | 0.88 | HTR6 (0.70) | HTTSMN1; SMN2PTGS2HTR6ALDH1A1 | |
| SCHEMBL17559302 | 0.86 | HTT (0.81) | HTTSMN1; SMN2HTR6SOS1LMNA | |
| SCHEMBL6123058 | 0.86 | HTT (0.81) | HTTSMN1; SMN2HTR6SOS1LMNA | |
| SCHEMBL146566 | 0.86 | HTT (0.81) | HTTSMN1; SMN2HTR6SOS1LMNA | |
| SCHEMBL11415437 | 0.86 | HTT (0.81) | HTTSMN1; SMN2HTR6SOS1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5480568-A | FOR LUBRICATING METAL CONTAINING SURFACES | THE DOW CHEMICAL COMPANY (US) | 1996-01-02 | — | — | US | claimed |