Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 2/20 | 0.70 |
| ▸ | PTGS2 | P35354 | 7/20 | 0.59 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7655181 | 1.00 | HTR6 (0.70) | HTR6PTGS2ENPP2SMN1; SMN2ALDH1A1 | |
| Methylphenylsulfone SCHEMBL1332357 | 0.89 | PTGS2 (0.62) | HTR6PTGS2ENPP2SMN1; SMN2ALDH1A1 | |
| SCHEMBL17548700 | 0.89 | ENPP2 (0.62) | HTR6PTGS2ENPP2ALDH1A1GAA | |
| Methylphenylsulfone SCHEMBL78253 | 0.89 | PTGS2 (0.62) | HTR6PTGS2ENPP2SMN1; SMN2ALDH1A1 | |
| SCHEMBL8941534 | 0.88 | HTT (0.68) | HTR6PTGS2SMN1; SMN2ALDH1A1HTT | |
| SCHEMBL17287077 | 0.88 | HTT (0.68) | HTR6PTGS2SMN1; SMN2ALDH1A1HTT | |
| (Phenylsulfonyl)Benzene SCHEMBL10870153 | 0.87 | HTR6 (0.82) | HTR6SMN1; SMN2ALDH1A1MAPTPOLB | |
| Methylphenylsulfone SCHEMBL5499087 | 0.87 | PTGS2 (0.60) | HTR6PTGS2ENPP2SMN1; SMN2ALDH1A1 | |
| SCHEMBL5051390 | 0.87 | HTR6 (0.93) | HTR6SMN1; SMN2ALDH1A1MAPTPOLB | |
| Methylphenylsulfone SCHEMBL28046614 | 0.84 | PTGS2 (0.58) | HTR6PTGS2ENPP2SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9670325-B2 | Nanomodified backbones for polyimides with difunctional and mixed-functionality endcaps | THE BOEING COMPANY (US) | 2017-06-06 | — | — | US | disclosed |
| US-20160208053-A1 | NANOMODIFIED BACKBONES FOR POLYIMIDES WITH DIFUNCTIONAL AND MIXED-FUNCTIONALITY ENDCAPS | THE BOEING COMPANY | 2016-07-21 | — | — | US | disclosed |