SCHEMBL17287077

SCHEMBL17287077

CS(=O)(=O)c1ccc(Oc2ccc(S(=O)(=O)c3ccc(Oc4ccc(S(=O)(=O)c5ccccc5)cc4)cc3)cc2)cc1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 5/20 0.68
SMN1; SMN2 Q16637 3/20 0.68
PTGS2 P35354 5/20 0.54
HTR6 P50406 1/20 0.54
SOS1 Q07889 1/20 0.53
LMNA P02545 4/20 0.53
TDP1 Q9NUW8 1/20 0.51
L3MBTL1 Q9Y468 1/20 0.51
PKM P14618 1/20 0.50
PTGS1 P23219 2/20 0.49
PGR P06401 2/20 0.49
MMP2 P08253 2/20 0.46
MMP9 P14780 2/20 0.46
MMP8 P22894 2/20 0.46
MMP12 P39900 2/20 0.46
MMP13 P45452 2/20 0.46
MMP14 P50281 2/20 0.46
MMP16 P51512 2/20 0.46
ALDH1A1 P00352 1/20 0.46
MMP3 P08254 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8941534 1.00 HTT (0.68) HTTSMN1; SMN2PTGS2HTR6SOS1
SCHEMBL7359540 0.90 SOS1 (0.64) HTTSMN1; SMN2PTGS2SOS1LMNA
SCHEMBL6848913 0.90 HTT (0.74) HTTSMN1; SMN2HTR6SOS1LMNA
SCHEMBL9323430 0.88 HTT (0.78) HTTSMN1; SMN2HTR6SOS1LMNA
SCHEMBL17936671 0.88 HTR6 (0.70) HTTSMN1; SMN2PTGS2HTR6ALDH1A1
SCHEMBL7655181 0.88 HTR6 (0.70) HTTSMN1; SMN2PTGS2HTR6ALDH1A1
SCHEMBL17559302 0.86 HTT (0.81) HTTSMN1; SMN2HTR6SOS1LMNA
SCHEMBL6123058 0.86 HTT (0.81) HTTSMN1; SMN2HTR6SOS1LMNA
SCHEMBL146566 0.86 HTT (0.81) HTTSMN1; SMN2HTR6SOS1LMNA
SCHEMBL11415437 0.86 HTT (0.81) HTTSMN1; SMN2HTR6SOS1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11111358-B2 Stabilizer compounds SOLVAY SPECIALTY POLYMERS USA, LLC (US) 2021-09-07 US disclosed
US-11111215-B2 Piperidine-based stabilizers and polymers end-capped with the same SOLVAY SPECIALTY POLYMERS USA, LLC (US) 2021-09-07 US disclosed
US-10954359-B2 Hydroxybenzophenone-based stabilizers and polymers end-capped with the same SOLVAY SPECIALTY POLYMERS USA, LLC (US) 2021-03-23 US disclosed
US-20200157312-A1 STABILIZER COMPOUNDS SOLVAY SPECIALTY POLYMERS USA, LLC (US) 2020-05-21 US disclosed
US-20200115340-A1 PIPERIDINE-BASED STABILIZERS AND POLYMERS END-CAPPED WITH THE SAME SOLVAY SPECIALTY POLYMERS USA, LLC (US) 2020-04-16 US disclosed
US-10400087-B2 Hydroxybenzophenone-based stabilizers and polymers end-capped with the same SOLVAY SPECIALTY POLYMERS USA, LLC (US) 2019-09-03 US disclosed
EP-3189099-B1 HYDROXYBENZOPHENONE-BASED STABILIZERS AND POLYMERS END-CAPPED WITH THE SAME SOLVAY SPECIALTY POLYMERS USA (US) 2018-07-11 EP disclosed
EP-3145910-B1 PIPERIDINE-BASED STABILIZERS AND POLYMERS END-CAPPED WITH THE SAME SOLVAY SPECIALTY POLYMERS USA (US) 2018-07-11 EP disclosed
US-20170240723-A1 Hydroxybenzophenone-based stabilizers and polymers end-capped with the same SOLVAY SPECIALTY POLYMERS USA, LLC (US) 2017-08-24 US disclosed
US-20170240723-A1 Hydroxybenzophenone-based stabilizers and polymers end-capped with the same SOLVAY SPECIALTY POLYMERS USA, LLC (US) 2017-08-24 US disclosed
US-20170204060-A1 Piperidine-based stabilizers and polymers end-capped with the same SOLVAY SPECIALTY POLYMERS USA, LLC (US) 2017-07-20 US disclosed
US-20170204060-A1 Piperidine-based stabilizers and polymers end-capped with the same SOLVAY SPECIALTY POLYMERS USA, LLC (US) 2017-07-20 US disclosed
US-20170190874-A1 Stabilizer Compounds SOLVAY SPECIALTY POLYMERS USA, LLC (US) 2017-07-06 US disclosed
US-20170190874-A1 Stabilizer Compounds SOLVAY SPECIALTY POLYMERS USA, LLC (US) 2017-07-06 US disclosed
WO-2016034689-A1 HYDROXYBENZOPHENONE-BASED STABILIZERS AND POLYMERS END-CAPPED WITH THE SAME SOLVAY SPECIALTY POLYMERS USA, LLC (US) 2016-03-10 WO disclosed
WO-2015177193-A1 STABILIZER COMPOUNDS SOLVAY SPECIALTY POLYMERS USA, LLC (US) 2015-11-26 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200157312-A1 STABILIZER COMPOUNDS HSF1, HEATR1, TBCA HTT 318/4885SMN1; SMN2 590/4885PTGS2 2024/4885
US-20170204060-A1 Piperidine-based stabilizers and polymers end-capped with the same CAPZA1, UNG, CAPZA2 HTT 247/4885SMN1; SMN2 1724/4885PTGS2 2726/4885
US-20170190874-A1 Stabilizer Compounds HSF1, HEATR1, TBCA HTT 318/4885SMN1; SMN2 590/4885PTGS2 2024/4885
US-10954359-B2 Hydroxybenzophenone-based stabilizers and polymers end-capped with the same TYR, HSPA1B, HSPH1 HTT 18/4885SMN1; SMN2 3109/4885PTGS2 2856/4885
US-10400087-B2 Hydroxybenzophenone-based stabilizers and polymers end-capped with the same TYR, HAO2, UNG HTT 16/4885SMN1; SMN2 3272/4885PTGS2 2777/4885
US-20200115340-A1 PIPERIDINE-BASED STABILIZERS AND POLYMERS END-CAPPED WITH THE SAME CAPZA1, UNG, CAPZA2 HTT 247/4885SMN1; SMN2 1724/4885PTGS2 2726/4885
US-11111358-B2 Stabilizer compounds HSF1, HEATR1, TBCA HTT 318/4885SMN1; SMN2 590/4885PTGS2 2024/4885
US-20170240723-A1 Hydroxybenzophenone-based stabilizers and polymers end-capped with the same TYR, HAO2, UNG HTT 16/4885SMN1; SMN2 3272/4885PTGS2 2777/4885
US-11111215-B2 Piperidine-based stabilizers and polymers end-capped with the same CAPZA1, UNG, CAPZA2 HTT 247/4885SMN1; SMN2 1724/4885PTGS2 2726/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.