Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SDHB | P21912 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | BCL2L1 | Q07817 | 3/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.39 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.39 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.39 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | EPAS1 | Q99814 | 2/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.38 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.38 |
| ▸ | RXRA | P19793 | 1/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8941535 | 0.87 | SDHB (0.42) | SDHBPTGS2BCL2L1MCL1SOS1 | |
| SCHEMBL8941549 | 0.86 | SOS1 (0.49) | SDHBSOS1NR3C1PGRAR | |
| SCHEMBL8941672 | 0.77 | SOS1 (0.51) | SDHBSOS1NR3C1PGRAR | |
| SCHEMBL8941636 | 0.77 | HTT (0.44) | PTGS2SOS1EPAS1PTPN1HTT | |
| SCHEMBL8941637 | 0.77 | PTPRZ1 (0.49) | SOS1EPAS1PTPN1HTTSMN1; SMN2 | |
| SCHEMBL19845789 | 0.74 | CYP1A1 (0.51) | BCL2L1MCL1GSTP1NR1H2SMN1; SMN2 | |
| SCHEMBL8941541 | 0.74 | PTPRZ1 (0.51) | SOS1NR3C1PGRARESR2 | |
| SCHEMBL8941500 | 0.74 | PTPRZ1 (0.51) | SOS1NR3C1PGRARESR2 | |
| SCHEMBL9842743 | 0.73 | GSTP1 (0.57) | PTGS2GSTP1ARNR1H2MAOA | |
| SCHEMBL8941531 | 0.72 | PTPRZ1 (0.50) | BCL2L1MCL1GSTP1SOS1PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5480568-A | FOR LUBRICATING METAL CONTAINING SURFACES | THE DOW CHEMICAL COMPANY (US) | 1996-01-02 | — | — | US | disclosed |