Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRZ1 | P23471 | 1/20 | 0.51 |
| ▸ | EPAS1 | Q99814 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.48 |
| ▸ | SOS1 | Q07889 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | MITF | O75030 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.46 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.46 |
| ▸ | SCN7A | Q01118 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8941500 | 1.00 | PTPRZ1 (0.51) | PTPRZ1EPAS1HTTTDP1L3MBTL1 | |
| SCHEMBL8941672 | 0.97 | SOS1 (0.51) | PTPRZ1EPAS1HTTTDP1L3MBTL1 | |
| SCHEMBL8941546 | 0.91 | NR3C1 (0.53) | PTPRZ1EPAS1HTTTDP1L3MBTL1 | |
| SCHEMBL11507063 | 0.89 | PTPRZ1 (0.61) | PTPRZ1EPAS1HTTPTPN1SOS1 | |
| SCHEMBL6000396 | 0.88 | PTGES (0.51) | L3MBTL1ALDH1A1GFERSCN7AKCNH2 | |
| SCHEMBL8941549 | 0.87 | SOS1 (0.49) | HTTTDP1L3MBTL1SOS1ALDH1A1 | |
| SCHEMBL8941529 | 0.83 | PTPRZ1 (0.56) | PTPRZ1EPAS1HTTPTPN1SOS1 | |
| SCHEMBL10952571 | 0.81 | EPAS1 (0.68) | PTPRZ1EPAS1PTPN1SOS1MEN1 | |
| SCHEMBL8941634 | 0.81 | HTT (0.57) | PTPRZ1HTTTDP1L3MBTL1PTPN1 | |
| SCHEMBL8941531 | 0.81 | PTPRZ1 (0.50) | PTPRZ1HTTPTPN1SOS1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5480568-A | FOR LUBRICATING METAL CONTAINING SURFACES | THE DOW CHEMICAL COMPANY (US) | 1996-01-02 | — | — | US | claimed |
| US-5480568-A | FOR LUBRICATING METAL CONTAINING SURFACES | THE DOW CHEMICAL COMPANY (US) | 1996-01-02 | — | — | US | disclosed |