Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.46 |
| ▸ | HTT | P42858 | 6/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | LMNA | P02545 | 5/20 | 0.46 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.42 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | XBP1 | P17861 | 1/20 | 0.41 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2758535 | 0.93 | HTT (0.51) | SMN1; SMN2HTTALDH1A1LMNAPTGS2 | |
| SCHEMBL8941539 | 0.93 | NR3C2 (0.54) | SMN1; SMN2HTTALDH1A1LMNANR3C2 | |
| SCHEMBL2758530 | 0.89 | PTGS2 (0.50) | SMN1; SMN2HTTPTGS2PTGS1 | |
| SCHEMBL11547843 | 0.85 | HTT (0.58) | SMN1; SMN2HTTALDH1A1LMNAPTGS2 | |
| SCHEMBL16417771 | 0.85 | ELANE (0.49) | SMN1; SMN2HTTALDH1A1LMNAPTGS2 | |
| SCHEMBL7990329 | 0.83 | PTGS2 (0.57) | PTGS2PTGS1 | |
| SCHEMBL19008827 | 0.80 | PKM (0.66) | SMN1; SMN2HTT | |
| SCHEMBL822791 | 0.80 | HTT (0.67) | SMN1; SMN2HTTALDH1A1LMNAMAPT | |
| SCHEMBL3020464 | 0.80 | HTT (0.62) | SMN1; SMN2HTTLMNANR3C2SOS1 | |
| SCHEMBL16378710 | 0.80 | PKM (0.66) | SMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5480568-A | FOR LUBRICATING METAL CONTAINING SURFACES | THE DOW CHEMICAL COMPANY (US) | 1996-01-02 | — | — | US | claimed |