Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | TSPO | P30536 | 1/20 | 0.35 |
| ▸ | PDE2A | O00408 | 2/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | TACR1 | P25103 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | RAD52 | P43351 | 1/20 | 0.32 |
| ▸ | MITF | O75030 | 1/20 | 0.32 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8941655 | 0.82 | KMT2A (0.37) | KMT2AMEN1TSPOPDE2APDE10A | |
| SCHEMBL8941625 | 0.72 | ELANE (0.37) | KMT2AMEN1PDE2APDE10ANPC1 | |
| SCHEMBL2880697 | 0.61 | ALDH1A1 (0.56) | KMT2AMEN1NPC1RAB9ATACR1 | |
| SCHEMBL6419274 | 0.59 | MEN1 (0.54) | KMT2AMEN1NPC1RAB9ATACR1 | |
| SCHEMBL8941633 | 0.58 | PLA2G7 (0.39) | KMT2AMEN1PDE2APDE10ANPC1 | |
| SCHEMBL23602743 | 0.58 | HSP90AA1 (0.55) | KMT2AMEN1TACR1HSP90AA1 | |
| SCHEMBL18520686 | 0.58 | BRAF (0.36) | KMT2APDE2APDE10APOLBGRM2 | |
| SCHEMBL27932801 | 0.57 | NAMPT (0.40) | NPC1TP53POLBALDH1A1HSP90AA1 | |
| SCHEMBL18520727 | 0.56 | PDE2A (0.43) | KMT2APDE2APDE10ANPC1RAB9A | |
| SCHEMBL19027274 | 0.56 | MEN1 (0.50) | KMT2AMEN1NPC1RAB9ATACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996019444-A1 | SULFONATE ACAT INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1996-06-27 | — | — | WO | disclosed |
| US-5510379-A | USEFUL FOR TREATING HYPERCHOLESTEROLEMIA AND ATHEROSCLEROSIS | WARNER-LAMBERT COMPANY (US) | 1996-04-23 | — | — | US | disclosed |