Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.36 |
| ▸ | TACR3 | P29371 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.34 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.33 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8941626 | 0.80 | ELANE (0.38) | ELANEGRM2TACR3KDM4ENPC1 | |
| SCHEMBL8941652 | 0.72 | KMT2A (0.37) | GRM2NPC1ALDH1A1TP53MEN1 | |
| SCHEMBL8941655 | 0.65 | KMT2A (0.37) | GRM2ALDH1A1TP53MEN1KMT2A | |
| SCHEMBL6139499 | 0.63 | EPHX2 (0.39) | ALDH1A1SMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL18520686 | 0.63 | BRAF (0.36) | ELANEGRM2HSD17B10KMT2APDE2A | |
| SCHEMBL10012543 | 0.62 | KMT2A (0.48) | KDM4EALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL8941633 | 0.61 | PLA2G7 (0.39) | GRM2KDM4ENPC1ALDH1A1HPGD | |
| SCHEMBL323736 | 0.61 | KMT2A (0.45) | ALDH1A1PKMSMN1; SMN2MEN1KMT2A | |
| SCHEMBL29364700 | 0.61 | KMT2A (0.45) | ALDH1A1PKMSMN1; SMN2MEN1KMT2A | |
| SCHEMBL323735 | 0.61 | KMT2A (0.45) | ALDH1A1PKMSMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996019444-A1 | SULFONATE ACAT INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1996-06-27 | — | — | WO | disclosed |
| US-5510379-A | USEFUL FOR TREATING HYPERCHOLESTEROLEMIA AND ATHEROSCLEROSIS | WARNER-LAMBERT COMPANY (US) | 1996-04-23 | — | — | US | disclosed |