Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | CRHBP | P24387 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.43 |
| ▸ | PRKCA | P17252 | 1/20 | 0.43 |
| ▸ | RASGRP3 | Q8IV61 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8941854 | 1.00 | MAPT (0.47) | MAPTALDH1A1MEN1KMT2ACRHBP | |
| SCHEMBL8941864 | 0.73 | HSD11B1 (0.43) | MEN1KMT2AGFERRAB9A | |
| SCHEMBL4392088 | 0.73 | ALDH1A1 (0.63) | MAPTALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL8941847 | 0.73 | ALDH1A1 (0.63) | MAPTALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL8116171 | 0.71 | RASGRP3 (0.54) | MAPTALDH1A1MEN1KMT2APRKCA | |
| SCHEMBL8115151 | 0.71 | RASGRP3 (0.54) | MAPTALDH1A1MEN1KMT2APRKCA | |
| SCHEMBL8115155 | 0.71 | RASGRP3 (0.54) | MAPTALDH1A1MEN1KMT2APRKCA | |
| SCHEMBL638794 | 0.70 | ALDH1A1 (0.47) | MAPTALDH1A1MEN1KMT2APRKCA | |
| SCHEMBL10116852 | 0.69 | MEN1 (0.57) | MAPTALDH1A1MEN1KMT2ACRHBP | |
| SCHEMBL8941897 | 0.69 | GRM2 (0.42) | MAPTALDH1A1MEN1KMT2AMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5521202-A | ANTIDIABETIC AGENTS | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 1996-05-28 | — | — | US | disclosed |
| EP-0645387-A1 | THIAZOLIDINE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 1995-03-29 | — | — | EP | disclosed |