Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 5/20 | 0.43 |
| ▸ | GRM2 | Q14416 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.39 |
| ▸ | CCR1 | P32246 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8941897 | 0.78 | GRM2 (0.42) | HSD11B1GRM2L3MBTL1MEN1KMT2A | |
| SCHEMBL8941935 | 0.77 | ALDH1A1 (0.44) | HSD11B1GRM2RAB9ASMN1; SMN2L3MBTL1 | |
| SCHEMBL4467710 | 0.77 | GRM2 (0.46) | HSD11B1GRM2RAB9ASMN1; SMN2GFER | |
| SCHEMBL8941860 | 0.73 | MAPT (0.47) | RAB9AGFERMEN1KMT2A | |
| SCHEMBL8941854 | 0.73 | MAPT (0.47) | RAB9AGFERMEN1KMT2A | |
| SCHEMBL8942109 | 0.72 | FFAR1 (0.50) | MEN1KMT2A | |
| SCHEMBL3592078 | 0.70 | HSD11B1 (0.43) | HSD11B1RAB9ASMN1; SMN2MEN1NPC1 | |
| SCHEMBL9677455 | 0.70 | MGLL (0.46) | GRM2L3MBTL1MGLLMEN1KMT2A | |
| SCHEMBL6260628 | 0.70 | MAOA (0.36) | HSD11B1GRM2SMN1; SMN2MEN1KMT2A | |
| SCHEMBL21944956 | 0.69 | SMN1; SMN2 (0.60) | HSD11B1RAB9ASMN1; SMN2L3MBTL1GFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5521202-A | ANTIDIABETIC AGENTS | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 1996-05-28 | — | — | US | disclosed |
| EP-0645387-A1 | THIAZOLIDINE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 1995-03-29 | — | — | EP | disclosed |