Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | FADS1 | O60427 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8941935 | 0.85 | ALDH1A1 (0.44) | GRM2MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL8942109 | 0.78 | FFAR1 (0.50) | MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL8941864 | 0.78 | HSD11B1 (0.43) | GRM2MEN1KMT2AL3MBTL1HSD11B1 | |
| SCHEMBL8941889 | 0.77 | PIM1 (0.56) | — | |
| SCHEMBL8942112 | 0.73 | SIRT2 (0.37) | GRM2MAPT | |
| SCHEMBL4467710 | 0.70 | GRM2 (0.46) | GRM2MEN1KMT2AMAPTKDM4E | |
| SCHEMBL8941860 | 0.69 | MAPT (0.47) | MEN1KMT2AALDH1A1MAPTMAOA | |
| SCHEMBL8941854 | 0.69 | MAPT (0.47) | MEN1KMT2AALDH1A1MAPTMAOA | |
| 1,4-Dimethoxybenzene SCHEMBL28617696 | 0.67 | MAOB (0.61) | MEN1KMT2AALDH1A1MAPTMAOA | |
| SCHEMBL30757515 | 0.67 | MAOB (0.61) | MEN1KMT2AALDH1A1MAPTMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5521202-A | ANTIDIABETIC AGENTS | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 1996-05-28 | — | — | US | disclosed |
| EP-0645387-A1 | THIAZOLIDINE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 1995-03-29 | — | — | EP | disclosed |