Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 3/20 | 0.56 |
| ▸ | PIM2 | Q9P1W9 | 3/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 8/20 | 0.55 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.47 |
| ▸ | CLK1 | P49759 | 1/20 | 0.47 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.47 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.47 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.47 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.47 |
| ▸ | PYGL | P06737 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8941935 | 0.82 | ALDH1A1 (0.44) | NPC1RAB9AHPGDCLK1DYRK1A | |
| SCHEMBL8941893 | 0.81 | CSNK2A2 (0.48) | PIM1PIM2NPC1RAB9AAKR1B1 | |
| SCHEMBL8941897 | 0.77 | GRM2 (0.42) | — | |
| SCHEMBL8942109 | 0.76 | FFAR1 (0.50) | HPGD | |
| SCHEMBL1247708 | 0.75 | PIM1 (1.00) | PIM1PIM2NPC1RAB9AAKR1B1 | |
| SCHEMBL2546911 | 0.75 | PIM1 (1.00) | PIM1PIM2NPC1RAB9AAKR1B1 | |
| SCHEMBL1247705 | 0.75 | PIM1 (1.00) | PIM1PIM2NPC1RAB9AAKR1B1 | |
| SCHEMBL1300546 | 0.72 | HPGD (1.00) | PIM1PIM2NPC1RAB9AAKR1B1 | |
| SCHEMBL1300545 | 0.72 | HPGD (1.00) | PIM1PIM2NPC1RAB9AAKR1B1 | |
| SCHEMBL5509146 | 0.71 | PIM1 (0.91) | PIM1PIM2NPC1RAB9AAKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5521202-A | ANTIDIABETIC AGENTS | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 1996-05-28 | — | — | US | disclosed |
| EP-0645387-A1 | THIAZOLIDINE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 1995-03-29 | — | — | EP | disclosed |