Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.48 |
| ▸ | CLK1 | P49759 | 1/20 | 0.48 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.48 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.48 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.48 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.48 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.48 |
| ▸ | PIM1 | P11309 | 2/20 | 0.42 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.42 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | NOD2 | Q9HC29 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ERO1A | Q96HE7 | 1/20 | 0.38 |
| ▸ | ADAMTS5 | Q9UNA0 | 2/20 | 0.36 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8941889 | 0.81 | PIM1 (0.56) | CSNK2A2CLK1CSNK2BCSNK2A1DYRK1A | |
| SCHEMBL8941935 | 0.75 | ALDH1A1 (0.44) | CLK1DYRK1ADYRK1BMEN1KMT2A | |
| SCHEMBL7466029 | 0.75 | CSNK2A1 (0.71) | CSNK2A2CLK1CSNK2BCSNK2A1DYRK1A | |
| SCHEMBL8942112 | 0.72 | SIRT2 (0.37) | GRM2 | |
| SCHEMBL8941897 | 0.70 | GRM2 (0.42) | MEN1KMT2AL3MBTL1GRM2 | |
| SCHEMBL8942109 | 0.70 | FFAR1 (0.50) | MEN1KMT2AHPGD | |
| SCHEMBL8615376 | 0.69 | CLK1 (1.00) | CSNK2A2CLK1CSNK2BCSNK2A1DYRK1A | |
| SCHEMBL9433321 | 0.67 | MMP13 (0.61) | AKR1B1MEN1KMT2APOLBADAMTS5 | |
| SCHEMBL8941864 | 0.66 | HSD11B1 (0.43) | MEN1KMT2ANPC1RAB9APOLB | |
| SCHEMBL8159453 | 0.64 | HPGD (0.60) | AKR1B1MEN1KMT2APOLBADAMTS5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5521202-A | ANTIDIABETIC AGENTS | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 1996-05-28 | — | — | US | disclosed |
| EP-0645387-A1 | THIAZOLIDINE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 1995-03-29 | — | — | EP | disclosed |