Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.44 |
| ▸ | GRM2 | Q14416 | 3/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | USP2 | O75604 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | CLK1 | P49759 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.36 |
| ▸ | MIF | P14174 | 1/20 | 0.35 |
| ▸ | XDH | P47989 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8941897 | 0.85 | GRM2 (0.42) | ALDH1A1GRM2HSD11B1MEN1KMT2A | |
| SCHEMBL8941889 | 0.82 | PIM1 (0.56) | CLK1DYRK1ADYRK1BHPGDATM | |
| SCHEMBL8941864 | 0.77 | HSD11B1 (0.43) | GRM2HSD11B1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL8941893 | 0.75 | CSNK2A2 (0.48) | GRM2MEN1KMT2ACLK1DYRK1A | |
| SCHEMBL8942109 | 0.75 | FFAR1 (0.50) | ALDH1A1MEN1KMT2ATDP1TSHR | |
| SCHEMBL8942112 | 0.72 | SIRT2 (0.37) | GRM2MAPTLMNA | |
| SCHEMBL4467710 | 0.69 | GRM2 (0.46) | GRM2HSD11B1MEN1KMT2ATDP1 | |
| SCHEMBL8470701 | 0.68 | ALDH1A1 (0.47) | ALDH1A1CYP2A6GRM2MEN1KMT2A | |
| SCHEMBL14996346 | 0.67 | ALDH1A1 (0.76) | ALDH1A1CYP2A6MEN1KMT2ATDP1 | |
| SCHEMBL19214413 | 0.67 | ALDH1A1 (0.76) | ALDH1A1CYP2A6TDP1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5521202-A | ANTIDIABETIC AGENTS | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 1996-05-28 | — | — | US | disclosed |
| EP-0645387-A1 | THIAZOLIDINE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 1995-03-29 | — | — | EP | disclosed |