Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | PDE7A | Q13946 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | ALPG | P10696 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | APOBEC3G | Q9HC16 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | KDM4A | O75164 | 1/20 | 0.43 |
| ▸ | TDP2 | O95551 | 1/20 | 0.43 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7458037 | 0.82 | CA2 (0.57) | ALDH1A1TSHRPDE7ASMN1; SMN2CRBN | |
| SCHEMBL7764834 | 0.82 | MEN1 (0.50) | ALDH1A1TSHRPDE7ASMN1; SMN2CRBN | |
| SCHEMBL7293883 | 0.79 | PDE7A (0.53) | ALDH1A1TSHRPDE7ASMN1; SMN2CRBN | |
| SCHEMBL8973221 | 0.79 | PTGS2 (0.49) | ALDH1A1PDE7ASMN1; SMN2CRBNMEN1 | |
| SCHEMBL1347642 | 0.78 | PTGS2 (0.49) | ALDH1A1PDE7ASMN1; SMN2CRBNMEN1 | |
| SCHEMBL8941933 | 0.78 | ALDH1A1 (0.67) | ALDH1A1TSHRPDE7ASMN1; SMN2CRBN | |
| SCHEMBL7293896 | 0.78 | PDE7A (0.51) | ALDH1A1TSHRPDE7ASMN1; SMN2CRBN | |
| SCHEMBL18614898 | 0.78 | PDE7A (0.51) | ALDH1A1TSHRPDE7ASMN1; SMN2CRBN | |
| SCHEMBL11270647 | 0.78 | PDE7A (0.51) | ALDH1A1TSHRPDE7ASMN1; SMN2CRBN | |
| SCHEMBL3386571 | 0.78 | MEN1 (0.53) | ALDH1A1TSHRPDE7ASMN1; SMN2CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5872300-A | Process for the preparation of 2-amino-6-chlorophenyl-alkylsulfanes, and 2-amino-6-chlorophenyl-isopropylsulfane | BAYER AKTIENGESELLSCHAFT (DE) | 1999-02-16 | — | — | US | claimed |
| WO-2023144793-A1 | POL THETA INHIBITORS | RHIZEN PHARMACEUTICALS AG (CH) | 2023-08-03 | — | — | WO | disclosed |
| WO-2023144793-A1 | POL THETA INHIBITORS | RHIZEN PHARMACEUTICALS AG (CH) | 2023-08-03 | — | — | WO | disclosed |
| US-5872300-A | Process for the preparation of 2-amino-6-chlorophenyl-alkylsulfanes, and 2-amino-6-chlorophenyl-isopropylsulfane | BAYER AKTIENGESELLSCHAFT (DE) | 1999-02-16 | — | — | US | disclosed |