Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.44 |
| ▸ | DPP4 | P27487 | 6/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.42 |
| ▸ | DRD1 | P21728 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9775934 | 0.89 | KMT2A (0.46) | ADRB2DPP4CHRM2DRD1KDM4E | |
| SCHEMBL7230077 | 0.88 | ADRB2 (0.50) | ADRB2DPP4CHRM2DRD1KDM4E | |
| SCHEMBL9775877 | 0.88 | ADRB2 (0.43) | ADRB2DPP4CHRM2DRD1KDM4E | |
| SCHEMBL8942162 | 0.88 | DPP4 (0.56) | DPP4CHRM2DRD1KDM4EALDH1A1 | |
| SCHEMBL9775893 | 0.87 | KDM4E (0.51) | ADRB2DPP4CHRM2DRD1KDM4E | |
| Water SCHEMBL8942213 | 0.87 | DPP4 (0.55) | DPP4CHRM2DRD1KDM4EALDH1A1 | |
| SCHEMBL8941959 | 0.84 | ADRB2 (0.43) | ADRB2DPP4CHRM2DRD1KDM4E | |
| SCHEMBL9786129 | 0.83 | DPP4 (0.44) | ADRB2DPP4CHRM2DRD1KDM4E | |
| SCHEMBL7228846 | 0.81 | ADRB2 (0.38) | ADRB2DPP4KDM4EHPGDCYP2C19 | |
| SCHEMBL5809336 | 0.81 | ADRB2 (0.53) | ADRB2DPP4CHRM2DRD1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5556861-A | 1,8 benzonaphthyridine derivatives and antimicrobial compositions | LABORATOIRE ROGER BELLON (FR) | 1996-09-17 | — | — | US | disclosed |