Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.42 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | CSF1R | P07333 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | ALB | P02768 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 2/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | DRD1 | P21728 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9775877 | 0.91 | ADRB2 (0.43) | KMT2AADRB2KDM4EALDH1A1HPGD | |
| SCHEMBL8941950 | 0.89 | ADRB2 (0.44) | ADRB2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL9775873 | 0.88 | KDM4E (0.52) | KDM4EALDH1A1HPGDHSD17B10KCNH2 | |
| SCHEMBL7230077 | 0.88 | ADRB2 (0.50) | KMT2AADRB2KDM4EALDH1A1HPGD | |
| SCHEMBL9775896 | 0.87 | ALDH1A1 (0.49) | KMT2AMEN1KDM4EMAPK10ALDH1A1 | |
| SCHEMBL9775893 | 0.86 | KDM4E (0.51) | ADRB2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL7228846 | 0.85 | ADRB2 (0.38) | KMT2AMEN1ADRB2KDM4EALDH1A1 | |
| SCHEMBL7131518 | 0.84 | ADRB2 (0.59) | KMT2AMEN1ADRB2KDM4EALDH1A1 | |
| SCHEMBL9775910 | 0.84 | ALDH1A1 (0.46) | KMT2AMEN1ADRB2KDM4EALDH1A1 | |
| SCHEMBL9786183 | 0.83 | KMT2A (0.42) | KMT2AMEN1KDM4EMAPK10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5004745-A | Benzo[1,8]naphthyridine derivatives, their preparation and the compositions which contain them | LABORATOIRE ROGER BELLON (FR) | 1991-04-02 | — | — | US | disclosed |