Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 7/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.37 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.37 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.37 |
| ▸ | FLT4 | P35916 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | RARB | P10826 | 1/20 | 0.37 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8942239 | 0.93 | ENPP2 (0.45) | TOP1ALDH1A1KDM4EENPP2KMT2A | |
| SCHEMBL8942049 | 0.92 | TOP1 (0.40) | TOP1ALDH1A1KDM4EENPP2EPHA2 | |
| SCHEMBL8941918 | 0.89 | TOP1 (0.41) | TOP1ALDH1A1KDM4EENPP2EPHA2 | |
| SCHEMBL8942072 | 0.89 | DPP4 (0.45) | TOP1ALDH1A1KDM4ELMNAHPGD | |
| SCHEMBL8942101 | 0.88 | TOP1 (0.39) | TOP1ALDH1A1KDM4EENPP2EPHA2 | |
| SCHEMBL8942266 | 0.85 | KDM4E (0.42) | TOP1ALDH1A1KDM4EENPP2LMNA | |
| SCHEMBL8942358 | 0.85 | ALDH1A1 (0.45) | TOP1ALDH1A1KDM4EEPHA2FLT4 | |
| SCHEMBL8942224 | 0.84 | ALDH1A1 (0.48) | TOP1ALDH1A1KDM4EEPHA2FLT4 | |
| SCHEMBL8941921 | 0.84 | ALDH1A1 (0.46) | TOP1ALDH1A1KDM4EEPHA2FLT4 | |
| SCHEMBL8942178 | 0.83 | ALDH1A1 (0.47) | TOP1ALDH1A1KDM4EEPHA2FLT4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5556861-A | 1,8 benzonaphthyridine derivatives and antimicrobial compositions | LABORATOIRE ROGER BELLON (FR) | 1996-09-17 | — | — | US | disclosed |