Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.38 |
| ▸ | FLT4 | P35916 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | RARB | P10826 | 1/20 | 0.38 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | ATP6V1B2 | P21281 | 1/20 | 0.37 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.37 |
| ▸ | EDNRA | P25101 | 1/20 | 0.37 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | XBP1 | P17861 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8941951 | 0.87 | DPP4 (0.47) | ALDH1A1EPHA2FLT4GSK3BRARB | |
| SCHEMBL8941925 | 0.83 | ALDH1A1 (0.42) | ALDH1A1EPHA2FLT4GSK3BRARB | |
| SCHEMBL8942081 | 0.79 | ALDH1A1 (0.44) | ALDH1A1EPHA2FLT4GSK3BRARB | |
| SCHEMBL9786233 | 0.79 | LMNA (0.46) | ALDH1A1EPHA2FLT4GSK3BKMT2A | |
| SCHEMBL8942174 | 0.78 | ALDH1A1 (0.49) | ALDH1A1EPHA2FLT4GSK3BRARB | |
| SCHEMBL8942358 | 0.78 | ALDH1A1 (0.45) | ALDH1A1EPHA2FLT4GSK3BRARB | |
| SCHEMBL8942224 | 0.78 | ALDH1A1 (0.48) | ALDH1A1EPHA2FLT4GSK3BRARB | |
| SCHEMBL8942026 | 0.77 | ALDH1A1 (0.44) | ALDH1A1EPHA2FLT4GSK3BRARB | |
| SCHEMBL9775969 | 0.77 | ALDH1A1 (0.67) | ALDH1A1KMT2ALMNACYP2C9ATP6V1B2 | |
| SCHEMBL8941921 | 0.77 | ALDH1A1 (0.46) | ALDH1A1EPHA2FLT4GSK3BRARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5556861-A | 1,8 benzonaphthyridine derivatives and antimicrobial compositions | LABORATOIRE ROGER BELLON (FR) | 1996-09-17 | — | — | US | disclosed |